Association of metabolic and inflammatory markers with polycystic ovarian syndrome (PCOS): an update

S Abraham Gnanadass, Y Divakar Prabhu… - Archives of Gynecology …, 2021 - Springer
Background Polycystic ovarian syndrome (PCOS) is the most prevalent metabolic disorder
in reproductive-age women. It is indeed a multifactorial condition evidenced by ovarian …

Ovulation: parallels with inflammatory processes

DM Duffy, CM Ko, M Jo, M Brannstrom… - Endocrine …, 2019 - academic.oup.com
The midcycle surge of LH sets in motion interconnected networks of signaling cascades to
bring about rupture of the follicle and release of the oocyte during ovulation. Many mediators …

An international consortium update: pathophysiology, diagnosis, and treatment of polycystic ovarian syndrome in adolescence

L Ibáñez, SE Oberfield, S Witchel, RJ Auchus… - Hormone research in …, 2017 - karger.com
This paper represents an international collaboration of paediatric endocrine and other
societies (listed in the Appendix) under the International Consortium of Paediatric …

Sex hormone-binding globulin (SHBG) as an early biomarker and therapeutic target in polycystic ovary syndrome

X Qu, R Donnelly - International journal of molecular sciences, 2020 - mdpi.com
Human sex hormone-binding globulin (SHBG) is a glycoprotein produced by the liver that
binds sex steroids with high affinity and specificity. Clinical observations and reports in the …

The Release of Peripheral Immune Inflammatory Cytokines Promote an Inflammatory Cascade in PCOS Patients via Altering the Follicular Microenvironment

Y Liu, H Liu, Z Li, H Fan, X Yan, X Liu, J Xuan… - Frontiers in …, 2021 - frontiersin.org
Background Hormones and immune imbalance are critical factors in polycystic ovary
syndrome (PCOS). The alternation of immune microenvironment of oocytes may play a …

Lipid metabolism and endometrial receptivity

T Yang, J Zhao, F Liu, Y Li - Human Reproduction Update, 2022 - academic.oup.com
BACKGROUND Obesity has now been recognized as a high-risk factor for reproductive
health. Although remarkable advancements have been made in ART, a considerable …

Exosomes as biomarkers for female reproductive diseases diagnosis and therapy

S Esfandyari, H Elkafas, RM Chugh, H Park… - International journal of …, 2021 - mdpi.com
Cell–cell communication is an essential mechanism for the maintenance and development
of various organs, including the female reproductive system. Today, it is well-known that the …

Ovarian follicular theca cell recruitment, differentiation, and impact on fertility: 2017 update

JAS Richards, YA Ren, N Candelaria… - Endocrine …, 2018 - academic.oup.com
The major goal of this review is to summarize recent exciting findings that have been
published within the past 10 years that, to our knowledge, have not been presented in detail …

The intersection of metformin and inflammation

LP Bharath, BS Nikolajczyk - American Journal of …, 2021 - journals.physiology.org
The biguanide metformin is the most commonly used antidiabetic drug. Recent studies show
that metformin not only improves chronic inflammation by improving metabolic parameters …

Pathophysiology of polycystic ovary syndrome revisited: Current understanding and perspectives regarding future research

M Harada - Reproductive medicine and biology, 2022 - Wiley Online Library
Background Polycystic ovary syndrome (PCOS) is the most common endocrine disorder
among reproductive‐age women and has lifelong effects on health. Methods In this review, I …