[HTML][HTML] Smart nanoparticles for cancer therapy
Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …
emerging as a promising drug delivery platform for precise cancer treatment. The field of …
[HTML][HTML] The biological applications of DNA nanomaterials: current challenges and future directions
W Ma, Y Zhan, Y Zhang, C Mao, X Xie… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …
biological applications as driven by DNA nanotechnology in the past decades, including …
In vitro selection of aptamers and their applications
MC DeRosa, A Lin, P Mallikaratchy… - Nature Reviews …, 2023 - nature.com
The introduction of the in vitro evolution method known as SELEX (systematic evolution of
ligands by exponential enrichment) more than 30 years ago led to the conception of …
ligands by exponential enrichment) more than 30 years ago led to the conception of …
[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …
treatment strategies, it remains a prominent cause of female mortality worldwide …
Gold nanoparticles as radiosensitizers in cancer radiotherapy
Y Chen, J Yang, S Fu, J Wu - International Journal of …, 2020 - Taylor & Francis
The rapid development of nanotechnology offers a variety of potential therapeutic strategies
for cancer treatment. High atomic element nanomaterials are often utilized as …
for cancer treatment. High atomic element nanomaterials are often utilized as …
[HTML][HTML] Recent advances in aptamer discovery and applications
Y Zhang, BS Lai, M Juhas - Molecules, 2019 - mdpi.com
Aptamers are short, single-stranded DNA, RNA, or synthetic XNA molecules that can be
developed with high affinity and specificity to interact with any desired targets. They have …
developed with high affinity and specificity to interact with any desired targets. They have …
[HTML][HTML] Aptamers 101: aptamer discovery and in vitro applications in biosensors and separations
Aptamers are single-stranded nucleic acids that bind and recognize targets much like
antibodies. Recently, aptamers have garnered increased interest due to their unique …
antibodies. Recently, aptamers have garnered increased interest due to their unique …
Aptamers as targeted therapeutics: current potential and challenges
Nucleic acid aptamers, often termed'chemical antibodies', are functionally comparable to
traditional antibodies, but offer several advantages, including their relatively small physical …
traditional antibodies, but offer several advantages, including their relatively small physical …
[HTML][HTML] Aptamers in the therapeutics and diagnostics pipelines
Aptamers are short single-stranded DNA or RNA oligonucleotides that can selectively bind
to small molecular ligands or protein targets with high affinity and specificity, by acquiring …
to small molecular ligands or protein targets with high affinity and specificity, by acquiring …