[HTML][HTML] Smart nanoparticles for cancer therapy

L Sun, H Liu, Y Ye, Y Lei, R Islam, S Tan… - Signal transduction and …, 2023 - nature.com
Smart nanoparticles, which can respond to biological cues or be guided by them, are
emerging as a promising drug delivery platform for precise cancer treatment. The field of …

[HTML][HTML] The biological applications of DNA nanomaterials: current challenges and future directions

W Ma, Y Zhan, Y Zhang, C Mao, X Xie… - Signal transduction and …, 2021 - nature.com
DNA, a genetic material, has been employed in different scientific directions for various
biological applications as driven by DNA nanotechnology in the past decades, including …

In vitro selection of aptamers and their applications

MC DeRosa, A Lin, P Mallikaratchy… - Nature Reviews …, 2023 - nature.com
The introduction of the in vitro evolution method known as SELEX (systematic evolution of
ligands by exponential enrichment) more than 30 years ago led to the conception of …

[HTML][HTML] Functionalized liposomes for targeted breast cancer drug delivery

J Nel, K Elkhoury, É Velot, A Bianchi, S Acherar… - Bioactive materials, 2023 - Elsevier
Despite the exceptional progress in breast cancer pathogenesis, prognosis, diagnosis, and
treatment strategies, it remains a prominent cause of female mortality worldwide …

Gold nanoparticles as radiosensitizers in cancer radiotherapy

Y Chen, J Yang, S Fu, J Wu - International Journal of …, 2020 - Taylor & Francis
The rapid development of nanotechnology offers a variety of potential therapeutic strategies
for cancer treatment. High atomic element nanomaterials are often utilized as …

[HTML][HTML] Recent advances in aptamer discovery and applications

Y Zhang, BS Lai, M Juhas - Molecules, 2019 - mdpi.com
Aptamers are short, single-stranded DNA, RNA, or synthetic XNA molecules that can be
developed with high affinity and specificity to interact with any desired targets. They have …

[HTML][HTML] Aptamers 101: aptamer discovery and in vitro applications in biosensors and separations

LF Yang, M Ling, N Kacherovsky, SH Pun - Chemical Science, 2023 - pubs.rsc.org
Aptamers are single-stranded nucleic acids that bind and recognize targets much like
antibodies. Recently, aptamers have garnered increased interest due to their unique …

Aptamers as targeted therapeutics: current potential and challenges

J Zhou, J Rossi - Nature reviews Drug discovery, 2017 - nature.com
Nucleic acid aptamers, often termed'chemical antibodies', are functionally comparable to
traditional antibodies, but offer several advantages, including their relatively small physical …

Aptamer-based targeted therapy

G Zhu, X Chen - Advanced drug delivery reviews, 2018 - Elsevier
Precision medicine holds great promise to harness genetic and epigenetic cues for targeted
treatment of a variety of diseases, ranging from many types of cancers, neurodegenerative …

[HTML][HTML] Aptamers in the therapeutics and diagnostics pipelines

H Kaur, JG Bruno, A Kumar, TK Sharma - Theranostics, 2018 - ncbi.nlm.nih.gov
Aptamers are short single-stranded DNA or RNA oligonucleotides that can selectively bind
to small molecular ligands or protein targets with high affinity and specificity, by acquiring …