[HTML][HTML] Role of PKM2-mediated immunometabolic reprogramming on development of cytokine storm
Z Liu, Y Le, H Chen, J Zhu, D Lu - Frontiers in immunology, 2021 - frontiersin.org
The cytokine storm is a marker of severity of various diseases and increased mortality. The
altered metabolic profile and energy generation of immune cells affects their activation …
altered metabolic profile and energy generation of immune cells affects their activation …
[HTML][HTML] Traditional Chinese medicine as a therapeutic option for cardiac fibrosis: pharmacology and mechanisms
X Li, L Li, W Lei, HZ Chua, Z Li, X Huang… - Biomedicine & …, 2021 - Elsevier
Cardiovascular diseases are one of the leading causes of death worldwide and cardiac
fibrosis is a common pathological process for cardiac remodeling in cardiovascular …
fibrosis is a common pathological process for cardiac remodeling in cardiovascular …
[HTML][HTML] Notoginsenoside R1-loaded mesoporous silica nanoparticles targeting the site of injury through inflammatory cells improves heart repair after myocardial …
H Li, J Zhu, Y Xu, F Mou, X Shan, Q Wang, B Liu… - Redox Biology, 2022 - Elsevier
Abstract Notoginsenoside R1 (NGR1) is the main monomeric component extracted from the
dried roots and rhizomes of Panax notoginseng, and exerts pharmacological action against …
dried roots and rhizomes of Panax notoginseng, and exerts pharmacological action against …
[HTML][HTML] miR-17-3p contributes to exercise-induced cardiac growth and protects against myocardial ischemia-reperfusion injury
Limited microRNAs (miRNAs, miRs) have been reported to be necessary for exercise-
induced cardiac growth and essential for protection against pathological cardiac …
induced cardiac growth and essential for protection against pathological cardiac …
[HTML][HTML] Crucial role of miR-433 in regulating cardiac fibrosis
Dysregulation of microRNAs has been implicated in many cardiovascular diseases
including fibrosis. Here we report that miR-433 was consistently elevated in three models of …
including fibrosis. Here we report that miR-433 was consistently elevated in three models of …
The nuclear melatonin receptor RORα is a novel endogenous defender against myocardial ischemia/reperfusion injury
B He, Y Zhao, L Xu, L Gao, Y Su… - Journal of pineal …, 2016 - Wiley Online Library
Circadian rhythm disruption or decrease in levels of circadian hormones such as melatonin
increases ischemic heart disease risk. The nuclear melatonin receptors ROR s are pivotally …
increases ischemic heart disease risk. The nuclear melatonin receptors ROR s are pivotally …
The discovery of Q-markers of Qiliqiangxin Capsule, a traditional Chinese medicine prescription in the treatment of chronic heart failure, based on a novel strategy of …
L He, Y Liu, K Yang, Z Zou, C Fan, Z Yao, Y Dai, K Li… - Phytomedicine, 2021 - Elsevier
Abstract Background Qiliqiangxin Capsule (QLQX), a traditional Chinese medicine (TCM)
prescription, is especially used for clinical treatment of chronic heart failure (CHF) in China …
prescription, is especially used for clinical treatment of chronic heart failure (CHF) in China …
LncRNA MHRT promotes cardiac fibrosis via miR-3185 pathway following myocardial infarction
M Lang, D Ou, Z Liu, Y Li, X Zhang… - International Heart …, 2021 - jstage.jst.go.jp
Long-chain noncoding RNA (lncRNA) is a new class of molecular regulators in heart
development and disease. However, the role of specific lncRNA in cardiac fibrosis remains …
development and disease. However, the role of specific lncRNA in cardiac fibrosis remains …
[HTML][HTML] Qiliqiangxin attenuates cardiac remodeling via inhibition of TGF-β1/Smad3 and NF-κB signaling pathways in a rat model of myocardial infarction
A Han, Y Lu, Q Zheng, J Zhang, YZ Zhao… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: Qiliqiangxin (QL), a traditional Chinese medicine, has been
demonstrated to be effective and safe for the treatment of chronic heart failure. Left …
demonstrated to be effective and safe for the treatment of chronic heart failure. Left …
Protective effect of Qiliqiangxin against Doxorubicin‐induced cardiomyopathy by suppressing excessive autophagy and apoptosis
Y Qin, C Lv, X Zhang, W Ruan, X Xu… - Cardiovascular …, 2022 - Wiley Online Library
Background. Doxorubicin (DOX) is one of the most potent and widely prescribed antitumor
agents; however, its clinical use is limited by cardiac side effects. In this study, we aimed to …
agents; however, its clinical use is limited by cardiac side effects. In this study, we aimed to …