Pancreatic beta-cell IL-22 receptor deficiency induces age-dependent dysregulation of insulin biosynthesis and systemic glucose homeostasis

H Sajiir, KY Wong, A Müller, S Keshvari, L Burr… - Nature …, 2024 - nature.com
The IL-22RA1 receptor is highly expressed in the pancreas, and exogenous IL-22 has been
shown to reduce endoplasmic reticulum and oxidative stress in human pancreatic islets and …