[HTML][HTML] Insulin in the regulation of the renin-angiotensin system: a new perspective on the mechanism of insulin resistance and diabetic complications

TS Zamolodchikova, SM Tolpygo… - Frontiers in …, 2024 - frontiersin.org
Insulin, a polypeptide hormone that is produced in the β-cells of the pancreatic islets of
Langerhans, has multifaceted effects on metabolism in virtually all tissues. Insulin facilitates …

Unraveling Light-Activated Insulin Action in Regulating Blood Glucose: New Photoactivatable Insight as a Novel Modality in Diabetes Management

F Nurkolis, R Kurniawan, E Wiyarta, RA Syahputra… - Molecules, 2024 - mdpi.com
Diabetes, particularly type 2 diabetes (T2D), is the main component of metabolic syndrome.
It is highly prevalent and has drastically increased with sedentary lifestyles, notably …

The association between triglyceride-glucose index and related parameters and risk of cardiovascular disease in American adults under different glucose metabolic …

Y Zhuang, L Qiu, D Han, Z Qiao, F Wang… - Diabetology & Metabolic …, 2024 - Springer
Background Cardiovascular disease (CVD) encompasses an array of cardiac and vascular
disorders, posing a significant threat to global health. It remains unclear whether there exists …

Insuline et dénutrition

R Bertrand, B Lambare, F Andreelli - Médecine des Maladies Métaboliques, 2022 - Elsevier
Sarcopenia is common among the elderly. Its pathophysiology is complex, and includes
lipotoxicity, oxidative stress and adipose tissue-derived inflammation. A reduction in physical …

Pathway and Network Analyses Identify Growth Factor Signaling and MMP9 as Potential Mediators of Mitochondrial Dysfunction in Severe COVID-19

Y Wang, K Schughart, TM Pelaia, T Chew… - International Journal of …, 2023 - mdpi.com
Patients with preexisting metabolic disorders such as diabetes are at a higher risk of
developing severe coronavirus disease 2019 (COVID-19). Mitochondrion, the very organelle …

From Oncogenes to Tumor Suppressors: The Dual Role of ncRNAs in Fibrosarcoma

I Kazmi, M Afzal, WH Almalki, SI Alzarea… - … -Research and Practice, 2024 - Elsevier
Fibrosarcoma is a challenging cancer originating from fibrous tissues, marked by aggressive
growth and limited treatment options. The discovery of non-coding RNAs (ncRNAs) …

Activation of NRF2 by epiberberine improves oxidative stress and insulin resistance in T2DM mice and IR-HepG2 cells in an AMPK dependent manner

S Zhang, S Zhang, Y Zhang, H Wang, Y Chen… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Phytochemical compounds offer a distinctive edge in
diabetes management, attributed to their multifaceted target mechanisms and minimal …

Endotoxin accelerates insulin amyloid formation and inactivates insulin signal transduction

QY Meng, ZX Lu, LX Liu, XZ Lu, WG Yu - Life Sciences, 2023 - Elsevier
Aims and objectives The aim of this study is to discuss the influence of endotoxin on insulin
amyloid formation, to provide guidance for therapeutic insulin preparation and storage …

The causal relationship between sarcopenia‐related traits and ischemic stroke: Insights from univariable and multivariable Mendelian randomization analyses

J Song, D Zhou, J Li, M Wang, L Jia… - CNS Neuroscience …, 2024 - Wiley Online Library
Aims The causal relationship between sarcopenia‐related traits and ischemic stroke (IS)
remains poorly understood. This study aimed to explore the causal impact of sarcopenia …

“Adjust Zang and arouse spirit” electroacupuncture ameliorates cognitive impairment by reducing endoplasmic reticulum stress in db/db mice

M Li, L Yao, M He, H Huang, H Zheng, S Ma… - Frontiers in …, 2023 - frontiersin.org
Introduction Diabetic cognitive impairment (DCI) is a chronic complication of the central
nervous system (CNS) caused by diabetes that affects learning and memory capacities over …