This guide was compiled after recommendations by the American Institute for Cancer
Research (AICR) Cancer Resource Advisory Council. It encompasses the AICR position on …

The vitamin D receptor binds the seco-steroid hormone 1, 25 (OH) 2D3 with high affinity and
controls gene programs that include a significant component of the control of serum calcium …

Induction of differentiation and apoptosis in cancer cells through ligands of nuclear hormone
receptors (NHRs) is a novel and promising approach to cancer therapy. All-trans-retinoic …

Glucagon-like peptide-1 (GLP-1) is an incretin hormone capable of restoring normal glucose
tolerance in aging glucose-intolerant Wistar rats. Whether the antidiabetic properties of GLP …

The production of high-affinity pathogenic autoantibodies in systemic lupus erythematosus
(SLE) may result from aberrant immune regulation. Since 1, 25 dihydroxy vitamin D3 (1, 25 …

Human C/EBPε is a newly cloned CCAAT/enhancer-binding transcription factor. Initial
studies indicated it may be an important regulator of human myelopoiesis. To elucidate the …

This study was undertaken to investigate the influence of the peroxisome proliferator-
activated receptor γ (PPARγ) agonists on the proliferation, apoptosis and tumorigenesis of …

The hormonally active form of vitamin D is 1α, 25-dihydroxyvitamin D3 [1, 25 (OH) 2D3],
which is a principal regulator of calcium homeostasis. It also affects hormone secretion, cell …

Vitamin D, a steroid hormone and exerts its biological effects through its active metabolite
1α, 25 dihydroxyvitamin D3 [1, 25 (OH) 2D3]. Like steroid hormones, 1, 25 (OH) 2D3 is …

As a steroid hormone that regulates mineral homeostasis and bone metabolism, 1α, 25-
dihydroxycholecalciferol (calcitriol) also has broad spectrum anti-tumor activities as …