The serotonergic system extends throughout the central nervous system (CNS) and the
gastrointestinal (GI) tract. In the CNS, serotonin (5-HT, 5-hydroxytryptamine) modulates a …

Abstract Treatment-resistant schizophrenia (TRS), the persistence of positive symptoms
despite≥ 2 trials of adequate dose and duration of antipsychotic medication with …

Neurotransmitter receptors support the propagation of signals in the human brain. How
receptor systems are situated within macro-scale neuroanatomy and how they shape …

Neurodevelopmental disorders are characterized by relatively early onset, with temporal
variations across conditions. These lifelong conditions lead to social and communication …

Secondary hypogammaglobulinemia (SHG) is characterized by reduced immunoglobulin
levels due to acquired causes of decreased antibody production or increased antibody loss …

We performed a meta-analysis to synthesize evidence on the efficacy and safety of physical
exercise as an add-on therapeutic intervention for quality of life (QoL), depressive symptoms …

Schizophrenia has been an evolutionary paradox: it has high heritability, but it is associated
with decreased reproductive success. The causal genetic variants underlying schizophrenia …

Schizophrenia is a heterogeneous psychiatric disorder, which can severely impact social
and professional functioning. Epidemiological and clinical studies show that schizophrenia …

Neurological diseases are recognized as major causes of disability and mortality worldwide.
Due to the dynamic progress of diseases such as Alzheimer's disease (AD), Parkinson's …

The NMDA-R hypofunction model of schizophrenia started with the clinical observation of
the precipitation of psychotic symptoms in patients with schizophrenia exposed to PCP or …