Background Schizophrenia (SCZ) is a chronic and severe mental illness with no cure so far.
Mendelian randomization (MR) is a genetic method widely used to explore etiologies of …

Introduction Current findings on multifactorial diseases with a complex pathomechanism
confirm that multi-target drugs are more efficient ways in treating them as opposed to single …

Deficits in cognition, physical, and social functions in adults with schizophrenia may become
salient with aging. While animal-assisted therapy (AAT) can benefit physical function in older …

Serotonin (5-HT) and inflammation are 2 major hypotheses in schizophrenia (SZ)
pathogenesis, both of which involve platelets. However, the association between platelet …

Schizophrenia is a chronic neuropsychiatric syndrome that significantly impacts daily
function and quality of life. All of the available guidelines suggest a combined treatment …

Mental illnesses are a global health challenge, and effective medicines are needed to treat
these conditions. Psychotropic drugs are commonly prescribed to manage mental disorders …

Schizophrenia (SCZ) is a prevalent cause of disability worldwide. Distinguished mainly by
psychosis, behavioral alterations could range from hallucinations to delusions. This …

Terpenoids are widely distributed in nature, especially in the plant kingdom, and exhibit
diverse pharmacological activities. In recent years, screening has revealed a wide variety of …

Membrane trafficking processes regulate G protein–coupled receptor (GPCR) activity.
Although class A GPCRs are capable of activating G proteins in a monomeric form, they can …

Objectives We conducted a comprehensive meta‐analysis of all available trials to evaluate
the efficacy and safety of estrogen and selective estrogen receptor modulators as adjunctive …