Heart failure (HF) is a global medical problem that characterizes poor prognosis and high
economic burden for the health system and family of the HF patients. Although modern …

Ischemic disease is among the deadliest and most disabling illnesses. Prominent examples
include myocardial infarction and stroke. Most, if not all, underlying pathological changes …

Astragaloside IV (AsIV), an active ingredient isolated from traditional Chinese medicine
astragalus membranaceus, is beneficial to cardiovascular health. This study aimed to …

Muscle wasting disease indications are among the most debilitating and often deadly
noncommunicable disease states. As a comorbidity, muscle wasting is associated with …

Cardiovascular diseases lead the mortality and morbidity disease metrics worldwide. A
multitude of chemical base modifications in ribonucleic acids (RNAs) have been linked with …

Background Advanced colorectal cancer (CRC) is often accompanied by the development of
liver metastases, as well as cachexia, a multi‐organ co‐morbidity primarily affecting skeletal …

Background Preeclampsia is a prominent risk factor for long‐term development of
cardiovascular disease. Although existing studies report a strong correlation between …

Peripartum cardiomyopathy (PPCM) is an idiopathic form of pregnancy-induced heart failure
associated with preeclampsia. Circulating factors in late pregnancy are thought to contribute …

Background Myostatin is a negative regulator of skeletal muscle and myocardial mass. The
relationship between myocardial ischemia and scar burden and levels of myostatin has not …

Pulmonary hypertension due to left heart disease (PH-LHD) is the most frequent
manifestation of PH but lacks any approved treatment. Activin receptor type IIA-Fc fusion …