Phase 1 dose escalation study of accelerated radiation therapy with concurrent chemotherapy for locally advanced lung cancer

CR Kelsey, S Das, L Gu, FR Dunphy III… - International Journal of …, 2015 - Elsevier
Purpose To determine the maximum tolerated dose of radiation therapy (RT) given in an
accelerated fashion with concurrent chemotherapy using intensity modulated RT. Methods …

A phase II trial of concurrent chemoradiation therapy followed by consolidation chemotherapy with oral etoposide and cisplatin for locally advanced inoperable non …

J Park, YC Ahn, H Kim, SH Lee, SH Park, KE Lee… - Lung Cancer, 2003 - Elsevier
We report a phase II study to evaluate the survival rate, response rate and toxicity of
concurrent chemoradiation therapy (CCRT) followed by consolidation chemotherapy (CT) …

Pilot study of accelerated radiotherapy with concurrent chemotherapy for stage III non-small cell lung cancer

M Machtay, C Washam, P Devine - Seminars in oncology, 2005 - Elsevier
The purpose of this pilot study was to determine the safety and feasibility of accelerated
fractionation (via concomitant boost) radiotherapy (XRT) with concurrent …

Treatment strategies for unresectable locally advanced non-small cell lung cancer in the real-life ESME cohort

N Girard, M Perol, G Simon, CA Valette, R Gervais… - Lung Cancer, 2021 - Elsevier
Background Cisplatin-based chemotherapy administered concurrently to thoracic radiation
therapy is the recommended treatment for fit patients with unresectable stage III NSCLC. The …

Cisplatin-docetaxel induction plus concurrent 3-D conformal radiotherapy and weekly chemotherapy for locally advanced non-small cell lung cancer patients: a phase …

M Poudenx, PY Bondiau, E Chamorey, N Venissac… - Oncology, 2012 - karger.com
Concurrent chemoradiotherapy (CHRT) is the standard of care for unresectable locally
advanced stage III non-small cell lung cancer. However, the optimal combination remains …

Combined chemo-radiotherapy for locally advanced non-small cell lung cancer: current status and future development

C Guida, P Maione, A Rossi, M Bareschino… - Critical reviews in …, 2008 - Elsevier
Currently, combinations of chemotherapy and radiotherapy are the standard treatment
approach for locally advanced NSCLC patients. Concomitant chemo-radiotherapy, although …

ACR Appropriateness Criteria® Nonsurgical Treatment for Non-Small-Cell Lung Cancer: Good Performance Status/Definitive Intent

RM Gewanter, KE Rosenzweig, JY Chang… - Current Problems in …, 2010 - Elsevier
The optimal strategy for the non-surgical definitive treatment of patients with good
performance status non-small cell lung cancer (mostly with locally advanced disease) has …

Combined modality therapy in the elderly population

LL Lin, SM Hahn - Current treatment options in oncology, 2009 - Springer
Opinion statement The incidence of cancer among older patients continues to rise. The use
of combined modality therapy has improved survival in a variety of malignancies, including …

Concurrent radiochemotherapy in the treatment of locally advanced non–small cell lung cancer

B Jeremic, M Machtay - Hematology/Oncology Clinics, 2004 - hemonc.theclinics.com
Locally advanced disease non–small cell lung cancer (NSCLC) usually refers to stage III
disease. After a recent move of T3 N0 to stage IIB, stage III still has a number of possible T …

Clinical perspectives on dose escalation for non–small-cell lung cancer

AJ Chang, JD Bradley - Clinical Lung Cancer, 2010 - Elsevier
Lung cancer remains the leading cause of cancer death in the United States. The standard
of care for patients with locally advanced non–small-cell lung cancer is radiation plus …