Inflammation, epigenetics, and metabolism converge to cell senescence and ageing: the regulation and intervention
X Zhu, Z Chen, W Shen, G Huang, JM Sedivy… - Signal transduction and …, 2021 - nature.com
Remarkable progress in ageing research has been achieved over the past decades.
General perceptions and experimental evidence pinpoint that the decline of physical …
General perceptions and experimental evidence pinpoint that the decline of physical …
Inflammaging and oxidative stress in human diseases: from molecular mechanisms to novel treatments
L Zuo, ER Prather, M Stetskiv, DE Garrison… - International journal of …, 2019 - mdpi.com
It has been proposed that a chronic state of inflammation correlated with aging known as
inflammaging, is implicated in multiple disease states commonly observed in the elderly …
inflammaging, is implicated in multiple disease states commonly observed in the elderly …
Age and age-related diseases: role of inflammation triggers and cytokines
IM Rea, DS Gibson, V McGilligan… - Frontiers in …, 2018 - frontiersin.org
Cytokine dysregulation is believed to play a key role in the remodeling of the immune
system at older age, with evidence pointing to an inability to fine-control systemic …
system at older age, with evidence pointing to an inability to fine-control systemic …
A proinflammatory gut microbiota increases systemic inflammation and accelerates atherosclerosis
E Brandsma, NJ Kloosterhuis, M Koster… - Circulation …, 2019 - Am Heart Assoc
Rationale: Several studies have suggested a role for the gut microbiota in inflammation and
atherogenesis. A causal relation relationship between gut microbiota, inflammation, and …
atherogenesis. A causal relation relationship between gut microbiota, inflammation, and …
[HTML][HTML] Pleotropic effects of polyphenols in cardiovascular system
Numerous epidemiological and clinical studies demonstrate the beneficial effects of
naturally occurring, polyphenol supplementations, on cardiovascular system. The present …
naturally occurring, polyphenol supplementations, on cardiovascular system. The present …
Inflammation, not cholesterol, is a cause of chronic disease
Since the Seven Countries Study, dietary cholesterol and the levels of serum cholesterol in
relation to the development of chronic diseases have been somewhat demonised. However …
relation to the development of chronic diseases have been somewhat demonised. However …
Food anthocyanins: Malvidin and its glycosides as promising antioxidant and anti-inflammatory agents with potential health benefits
A Merecz-Sadowska, P Sitarek, T Kowalczyk, K Zajdel… - Nutrients, 2023 - mdpi.com
Anthocyanins are flavonoid compounds that are abundantly present in fruits and vegetables.
These compounds contribute to the color of these foods and offer various health benefits to …
These compounds contribute to the color of these foods and offer various health benefits to …
Macrophages and foam cells: Brief overview of their role, linkage, and targeting potential in atherosclerosis
AV Poznyak, NG Nikiforov, AV Starodubova… - Biomedicines, 2021 - mdpi.com
Atherosclerosis is still one of the main causes of death around the globe. This condition
leads to various life-threatening cardiovascular complications. However, no effective …
leads to various life-threatening cardiovascular complications. However, no effective …
[HTML][HTML] GLP-1 receptor agonists and reduction of cardiometabolic risk: Potential underlying mechanisms
Type 2 diabetes mellitus (T2DM) is a metabolic condition with an elevated impact on
cardiovascular (CV) risk. The innovative therapeutic approaches for T2DM-incretin-based …
cardiovascular (CV) risk. The innovative therapeutic approaches for T2DM-incretin-based …
Ferulic, sinapic, 3, 4-dimethoxycinnamic acid and indomethacin derivatives with antioxidant, anti-inflammatory and hypolipidemic functionality
P Theodosis-Nobelos, G Papagiouvannis, EA Rekka - Antioxidants, 2023 - mdpi.com
A series of thiomorpholine and cinnamyl alcohol derivatives, conjugated with cinnamic acid-
containing moieties, such as ferulic acid, sinapic acid and 3, 4-dimethoxycinnamic acid …
containing moieties, such as ferulic acid, sinapic acid and 3, 4-dimethoxycinnamic acid …