This short review aims at revisiting some of the putative mechanisms of tinnitus. Cochlear-
type tinnitus is suggested to result from aberrant activity generated before or at the cochlear …

Noise accounts for one-third of hearing loss worldwide. Regretfully, noise-induced hearing
loss (NIHL) is deemed to be irreversible due to the elusive pathogenic mechanisms that …

Tinnitus is not a single disease but a group of different diseases with different pathologies
and therefore different treatments. Regarding tinnitus as a single disease is hampering …

Background: Accumulating evidence suggests that tinnitus may occur despite normal
auditory sensitivity, probably linked to partial degeneration of the cochlear nerve and …

Objective To evaluate the efficacy and safety of intratympanic AM-101 in patients with
persistent acute inner ear tinnitus after acute acoustic trauma, idiopathic sudden …

Disorders of the eye and ear severely influence the life of millions of people worldwide, but
management strategies for these disorders present the challenge primarily for the design of …

Objective To evaluate the safety and tolerability of repeated intratympanic administration of
the gel-formulated NMDA receptor antagonist AM-101 in acute patients with inner ear …

Disorders of the ear severely impact the quality of life of millions of people, but the treatment
of these disorders is an ongoing, but often overlooked challenge particularly in terms of …

Inhibition of cochlear N-methyl-d-aspartate (NMDA) receptors with AM-101, a small
molecule antagonist delivered by intratympanic injection, represents a novel approach to …

Aim The aim of this study was to assess the efficacy and feasibility of virtual follow-up in
patients who have undergone intratympanic steroid injection for treatment of tinnitus during …