Time and temperature dependence of the binding of 3H-dihydroalprenolol (3H-DHA) to beta-
adrenergic receptors in rat cerebral cortex is described. The kinetic data obtained suggest …

1. The effect of temperature on the binding of agonists and antagonists to cardiac muscarinic
receptor sites was investigated. 2. Compared to 37 degrees C, carbachol-[3H] QNB and …

Abstract The relationship between [3 H](−)-quinuclinidyl benzilate ([3 H](−) QNB) binding
and muscarinic cholinoceptors in the myometrium of the oestrogen treated rabbit was …

A method was developed to determine the affinities of antimuscarinic drugs at m 1
receptors.[3 H](±)-Telenzepine served as radioligand in crude preparations of calf superior …

Kinetic analysis of the interaction of four N-substituted nortropane derivatives with the
dopamine transporter was made to characterize the mechanism of the binding process. The …

The kinetics of 2′-deoxyadenosine-5′-O-(1-thiotriphosphate)([35S] dATPαS) interaction
with membrane fragments of transfected astrocytoma 1321N1 cells, expressing human …

Publisher Summary This chapter describes the structure and function of muscarinic
receptors (mAchR). The results from several laboratories regarding the structure and …

A series of N‐substituted tropane derivatives were synthesized and their interactions with
the dopamine transporter were analyzed using kinetic methods. This series was designed to …

Similar dynamics of G-protein coupled receptors molecules in response to antagonist binding -
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Abstract l-Quinuclidinyl benzilate is undoubtedly the most widely used radioactive reporter
ligand for studies on muscarinic receptor. In the present Commentary the kinetic aspects of …