Myosin-X (Myo10) is an unconventional myosin with MyTH4-FERM domains that is best
known for its striking localization to the tips of filopodia and its ability to induce filopodia …

Myosin VI is the only type of myosin motor known to move toward the minus ends of actin
filaments. This reversal in the direction of its movement is in part a consequence of the …

This work employed the model protein β-lactoglobulin (BLG) to investigate the contribution
of microstructural changes to regulating the interaction patterns between protein and flavor …

Current single-particle cryo-electron microscopy (cryo-EM) techniques can produce images
of large protein assemblies and macromolecular complexes at atomic level detail without the …

We test a range of standard generalized Born (GB) models and protein force fields for a set
of five experimentally characterized, designed peptides comprising alternating blocks of …

Using a combination of ultraviolet circular dichroism, temperature-jump transient-infrared
spectroscopy, and molecular dynamics simulations, we investigate the effect of salt bridges …

Linkers play critical roles in the construction of synthetic protein switches and sensors as
they functionally couple a receptor with an actuator. With an increasing number of molecular …

The noncovalent forces that stabilize protein structures are not fully understood. One way to
address this is to study equilibria between unfolded states and α-helices in peptides …

The swinging crossbridge hypothesis states that energy from ATP hydrolysis is transduced
to mechanical movement of the myosin head while bound to actin. The light chain-binding …

Intracellular cargo transport by kinesin family motor proteins is crucial for many cellular
processes, particularly vesicle transport in axons and dendrites. In a number of cases, the …