[HTML][HTML] Dendrimers in the context of nanomedicine

AP Dias, S da Silva Santos, JV da Silva… - International journal of …, 2020 - Elsevier
Dendrimers are globular structures, presenting an initiator core, repetitive layers starting
radially from the core and terminal groups on the surface, resembling tree architecture …

[HTML][HTML] New advances in general biomedical applications of PAMAM dendrimers

RV Araújo, SS Santos, E Igne Ferreira, J Giarolla - Molecules, 2018 - mdpi.com
Dendrimers are nanoscopic compounds, which are monodispersed, and they are generally
considered as homogeneous. PAMAM (polyamidoamine) was introduced in 1985, by …

Dendrimers as efficient nanocarriers for the protection and delivery of bioactive phytochemicals

M Yousefi, A Narmani, SM Jafari - Advances in colloid and interface science, 2020 - Elsevier
The genesis of dendrimers can be considered as a revolution in nano-scaled bioactive
delivery systems. These structures possess a unique potential in encapsulating/entrapping …

Dendrimers in combination with natural products and analogues as anti-cancer agents

S Mignani, J Rodrigues, H Tomas… - Chemical Society …, 2018 - pubs.rsc.org
For the first time, an overview of dendrimers in combination with natural products and
analogues as anti-cancer agents is presented. This reflects the development of drug delivery …

Targeted delivery of nutraceuticals derived from food for the treatment of obesity and its related complications

Z Dai, Y Zhang, Y Meng, S Li, Z Suonan, Y Sun, J Ji… - Food Chemistry, 2023 - Elsevier
Nutraceuticals which are abundant in foods have attracted much attention due to their
bioactive activities of anti-obesity, anti-hyperlipidemia and anti-atherosclerosis …

Nanotechnological strategies for systemic microbial infections treatment: A review

MA dos Santos Ramos, KC Dos Santos… - International Journal of …, 2020 - Elsevier
Systemic infections is one of the major causes of mortality worldwide, and a shortage of drug
approaches applied for the rapid and necessary treatment contribute to increase the levels …

Dendrimer-based delivery of macromolecules for the treatment of brain tumor

H Choudhury, M Pandey, R Mohgan, JSJ Jong… - Biomaterials …, 2022 - Elsevier
Brain tumor represents the most lethal form of cancer with the highest mortality and morbidity
rates irrespective of age and sex. Advancements in macromolecule-based therapy (such as …

[HTML][HTML] N-acetylcysteine pharmacology and applications in rare diseases—Repurposing an old antioxidant

SA Sahasrabudhe, MR Terluk, RV Kartha - Antioxidants, 2023 - mdpi.com
N-acetylcysteine (NAC), a precursor of cysteine and, thereby, glutathione (GSH), acts as an
antioxidant through a variety of mechanisms, including oxidant scavenging, GSH …

Pharmaceutical perspective on the translational hurdles of phytoconstituents and strategies to overcome

N Sayed, A Khurana, C Godugu - Journal of Drug Delivery Science and …, 2019 - Elsevier
Nature is a rich source of lead molecules for drug discovery and development. However, the
irony is that despite this wealth, only a handful of molecules from the plant origin have …

[HTML][HTML] Potential of nanoformulations in malaria treatment

JB Chaves, B Portugal Tavares de Moraes… - Frontiers in …, 2022 - frontiersin.org
Malaria is caused by the protozoan Plasmodium sp and affects millions of people worldwide.
Its clinical form ranges from asymptomatic to potentially fatal and severe. Current treatments …