Abstract In 2003 Rubenstein and Merzenich hypothesized that some forms of Autism (ASD)
might be caused by a reduction in signal-to-noise in key neural circuits, which could be the …

Malformations of cortical development are a group of rare disorders commonly manifesting
with developmental delay, cerebral palsy or seizures. The neurological outcome is …

Brain organoids are an exciting new technology with the potential to significantly change
how diseases of the brain are understood and treated. These three‐dimensional neural …

Malformations of cortical development encompass heterogeneous groups of structural brain
anomalies associated with complex neurodevelopmental disorders and diverse genetic and …

Parvalbumin-positive neurons are the largest class of GABAergic, inhibitory neurons in the
central nervous system. In the cortex, these fast-spiking cells provide feedforward and …

The analysis of animal models of neurological disease has been instrumental in furthering
our understanding of neurodevelopment and brain diseases. However, animal models are …

Transcranial focused ultrasound (FUS) stimulation under MRI guidance, coupled with
functional MRI (fMRI) monitoring of effects, offers a precise, noninvasive technology to …

GABAergic interneurons of the parvalbumin-positive fast-spiking basket cells subtype (PV
INs) are important regulators of cortical network excitability and of gamma oscillations …

This review accompanies a 2016 SFN mini-symposium presenting examples of current
studies that address a central question: How do neural stem cells (NSCs) divide in different …

Understanding the developmental etiology of autistic spectrum disorders, attention
deficit/hyperactivity disorder and schizophrenia remains a major challenge for establishing …