Clinical imaging in regenerative medicine

AV Naumova, M Modo, A Moore, CE Murry… - Nature …, 2014 - nature.com
In regenerative medicine, clinical imaging is indispensable for characterizing damaged
tissue and for measuring the safety and efficacy of therapy. However, the ability to track the …

Diffusion MRI in the heart

C Mekkaoui, TG Reese, MP Jackowski… - NMR in …, 2017 - Wiley Online Library
Diffusion MRI provides unique information on the structure, organization, and integrity of the
myocardium without the need for exogenous contrast agents. Diffusion MRI in the heart …

Programming cellular alignment in engineered cardiac tissue via bioprinting anisotropic organ building blocks

JH Ahrens, SGM Uzel, M Skylar‐Scott… - Advanced …, 2022 - Wiley Online Library
The ability to replicate the 3D myocardial architecture found in human hearts is a grand
challenge. Here, the fabrication of aligned cardiac tissues via bioprinting anisotropic organ …

Hypoxia treatment reverses neurodegenerative disease in a mouse model of Leigh syndrome

M Ferrari, IH Jain, O Goldberger… - Proceedings of the …, 2017 - National Acad Sciences
The most common pediatric mitochondrial disease is Leigh syndrome, an episodic,
subacute neurodegeneration that can lead to death within the first few years of life, for which …

Second‐order motion‐compensated spin echo diffusion tensor imaging of the human heart

CT Stoeck, C von Deuster, M Genet… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose Myocardial microstructure has been challenging to probe in vivo. Spin echo–based
diffusion‐weighted sequences allow for single‐shot acquisitions but are highly sensitive to …

Mapping immune cell infiltration using restricted diffusion MRI

FC Yeh, L Liu, TK Hitchens… - Magnetic resonance in …, 2017 - Wiley Online Library
Purpose Diffusion MRI provides a noninvasive way to assess tissue microstructure. Based
on diffusion MRI, we propose a model‐free method called restricted diffusion imaging (RDI) …

Spin echo versus stimulated echo diffusion tensor imaging of the in vivo human heart

C von Deuster, CT Stoeck, M Genet… - Magnetic resonance …, 2016 - Wiley Online Library
Purpose To compare signal‐to‐noise ratio (SNR) efficiency and diffusion tensor metrics of
cardiac diffusion tensor mapping using acceleration‐compensated spin‐echo (SE) and …

Dual-phase cardiac diffusion tensor imaging with strain correction

CT Stoeck, A Kalinowska, C Von Deuster, J Harmer… - PloS one, 2014 - journals.plos.org
Purpose In this work we present a dual-phase diffusion tensor imaging (DTI) technique that
incorporates a correction scheme for the cardiac material strain, based on 3D myocardial …

Cardiovascular magnetic resonance imaging for sequential assessment of cardiac fibrosis in mice: technical advancements and reverse translation

YC Chen, G Zheng, DG Donner… - American Journal …, 2024 - journals.physiology.org
Cardiovascular magnetic resonance (CMR) imaging has become an essential technique for
the assessment of cardiac function and morphology, and is now routinely used to monitor …

Myocardial scar delineation using diffusion tensor magnetic resonance tractography

C Mekkaoui, MP Jackowski, WJ Kostis… - Journal of the …, 2018 - Am Heart Assoc
Background Late gadolinium enhancement (LGE) is the current standard for myocardial scar
delineation. In this study, we introduce the tractographic propagation angle (PA), a metric of …