[HTML][HTML] The contribution of Neanderthal introgression to modern human traits

PF Reilly, A Tjahjadi, SL Miller, JM Akey, S Tucci - Current Biology, 2022 - cell.com
Neanderthals, our closest extinct relatives, lived in western Eurasia from 400,000 years ago
until they went extinct around 40,000 years ago. DNA retrieved from ancient specimens …

The lingering effects of Neanderthal introgression on human complex traits

X Wei, CR Robles, A Pazokitoroudi, A Ganna, A Gusev… - elife, 2023 - elifesciences.org
The genetic variants introduced into the ancestors of modern humans from interbreeding
with Neanderthals have been suggested to contribute an unexpected extent to complex …

Reconstructing the 3D genome organization of Neanderthals reveals that chromatin folding shaped phenotypic and sequence divergence

E McArthur, DC Rinker, EN Gilbertson, G Fudenberg… - Biorxiv, 2022 - biorxiv.org
Abstract Changes in gene regulation were a major driver of the divergence of archaic
hominins (AHs)—Neanderthals and Denisovans—and modern humans (MHs). The three …

[HTML][HTML] Functional and molecular characterization of suicidality factors using phenotypic and genome-wide data

A Quintero Reis, BA Newton, R Kessler… - Molecular …, 2023 - nature.com
Genome-wide association studies (GWAS) of suicidal thoughts and behaviors support the
existence of genetic contributions. Continuous measures of psychiatric disorder symptom …

The contribution of the 3D genome to gene regulation, human evolution, and disease

E McArthur - 2022 - search.proquest.com
Interpreting the consequences of the millions of genetic variants present in each human
genome requires an understanding of human evolutionary history coupled with mechanistic …