Arachidonic acid metabolism and kidney inflammation

T Wang, X Fu, Q Chen, JK Patra, D Wang… - International journal of …, 2019 - mdpi.com
As a major component of cell membrane lipids, Arachidonic acid (AA), being a major
component of the cell membrane lipid content, is mainly metabolized by three kinds of …

[HTML][HTML] The anti-PLA2R antibody in membranous nephropathy: what we know and what remains a decade after its discovery

AE van de Logt, M Fresquet, JF Wetzels, P Brenchley - Kidney international, 2019 - Elsevier
The discovery in 2009 of the M-type phospholipase A2 receptor (PLA2R) as the primary
target in membranous nephropathy (MN) greatly advanced basic and clinical research …

Advances in the management of primary membranous nephropathy and rituximab-refractory membranous nephropathy

M Teisseyre, M Cremoni, S Boyer-Suavet… - Frontiers in …, 2022 - frontiersin.org
Primary membranous nephropathy (pMN) is an auto-immune disease characterized by auto-
antibodies targeting podocyte antigens resulting in activation of complement and damage to …

Novel ELISA for thrombospondin type 1 domain-containing 7A autoantibodies in membranous nephropathy

C Zaghrini, B Seitz-Polski, J Justino, G Dolla, C Payre… - Kidney International, 2019 - Elsevier
Autoantibodies against phospholipase A2 receptor 1 (PLA2R1) and thrombospondin type 1
domain-containing 7A (THSD7A) are emerging as biomarkers to classify membranous …

Autoantibodies in the diagnosis, monitoring, and treatment of membranous nephropathy

V Tesar, Z Hruskova - Frontiers in Immunology, 2021 - frontiersin.org
The discovery of anti-podocyte antibodies in primary membranous nephropathy (MN) has
revolutionized our approach toward the diagnosis and treatment of this disease. Evaluation …

Efficacy and safety of different immunosuppressive therapies in patients with membranous nephropathy and high PLA2R antibody titer

L Deng, Q Huang, J Wang, K Luo, J Liu… - Frontiers in …, 2022 - frontiersin.org
Background: This study aimed to evaluate clinical features and prognosis and therapy
option of patients with different risk ranks based on antibody against the M-type …

Novel biomarkers in membranous nephropathy

Q Liu, J Liu, B Lin, Y Zhang, M Ma, M Yang… - Frontiers in …, 2022 - frontiersin.org
Membranous nephropathy (MN) is the main cause of adult nephrotic syndrome (NS). The
pathogenesis of MN is complex and involves subepithelial immune complex deposition …

Rituximab immunomonitoring predicts remission in membranous nephropathy

M Teisseyre, M Cremoni, S Boyer-Suavet… - Frontiers in …, 2021 - frontiersin.org
Primary membranous nephropathy (pMN) is an autoimmune kidney disease and a common
cause of nephrotic syndrome in adults. Rituximab is becoming a first line therapy for patients …

[HTML][HTML] Anti-PLA2R1 antibodies as prognostic biomarker in membranous nephropathy

AE van De Logt, J Justino, CH Vink… - Kidney International …, 2021 - Elsevier
Introduction Personalized treatment for patients with membranous nephropathy requires
accurate prediction of the disease course at an early stage. In this study, we evaluated the …

Membranous nephropathy posttransplantation: an update of the pathophysiology and management

J Leon, MJ Pérez-Sáez, I Batal, LH Beck Jr… - …, 2019 - journals.lww.com
Membranous nephropathy (MN) is a common cause of nephrotic syndrome after
transplantation and is associated with an increased risk of allograft loss. MN may occur …