Mass spectrometry based targeted protein quantification: methods and applications

S Pan, R Aebersold, R Chen, J Rush… - Journal of proteome …, 2009 - ACS Publications
The recent advance in technology for mass spectrometry-based targeted protein
quantification has opened new avenues for a broad range of proteomic applications in …

Biomarkers for Alzheimer's disease and other forms of dementia: clinical needs, limitations and future aspects

A Cedazo-Minguez, B Winblad - Experimental gerontology, 2010 - Elsevier
An early diagnosis of Alzheimer's disease (AD) and other types of dementia-causing
disorders is vital in order to achieve effective treatments. Fortunately, in the recent years the …

Proteomics of human cerebrospinal fluid: discovery and verification of biomarker candidates in neurodegenerative diseases using quantitative proteomics

AC Kroksveen, JA Opsahl, TT Aye, RJ Ulvik… - Journal of …, 2011 - Elsevier
There is an urgent need for novel biomarkers that can be used to improve the diagnosis,
predict the disease progression, improve our understanding of the pathology or serve as …

[HTML][HTML] Bilingualism and cognitive reserve: a critical overview and a plea for methodological innovations

N Calvo, AM García, L Manoiloff… - Frontiers in aging …, 2016 - frontiersin.org
The decline of cognitive skills throughout healthy or pathological aging can be slowed down
by experiences which foster cognitive reserve (CR). Recently, some studies on Alzheimer's …

Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases

GN Yin, HW Lee, JY Cho, K Suk - Brain research, 2009 - Elsevier
Neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease
(PD), are characterized by progressive loss of cognitive function, dementia, and problems …

Diffusion-MRI in neurodegenerative disorders

J Goveas, L O'Dwyer, M Mascalchi, M Cosottini… - Magnetic resonance …, 2015 - Elsevier
The ability to image the whole brain through ever more subtle and specific
methods/contrasts has come to play a key role in understanding the basis of brain …

Biomarker discovery in neurodegenerative diseases: a proteomic approach

M Shi, WM Caudle, J Zhang - Neurobiology of disease, 2009 - Elsevier
Biomarkers for neurodegenerative disorders are essential to facilitate disease diagnosis,
ideally at early stages, monitor disease progression, and assess response to existing and …

The effect of preanalytical factors on stability of the proteome and selected metabolites in cerebrospinal fluid (CSF)

T Rosenling, CL Slim, C Christin, L Coulier… - Journal of proteome …, 2009 - ACS Publications
To standardize the use of cerebrospinal fluid (CSF) for biomarker research, a set of stability
studies have been performed on porcine samples to investigate the influence of common …

[HTML][HTML] MS-based glycomics: An analytical tool to assess nervous system diseases

W Peng, F Kobeissy, S Mondello, C Barsa… - Frontiers in …, 2022 - frontiersin.org
Neurological diseases affect millions of peopleochemistryorldwide and are continuously
increasing due to the globe's aging population. Such diseases affect the nervous system …

A combined dataset of human cerebrospinal fluid proteins identified by multi‐dimensional chromatography and tandem mass spectrometry

S Pan, D Zhu, JF Quinn, ER Peskind, TJ Montine… - …, 2007 - Wiley Online Library
Human cerebrospinal fluid (CSF) is an important source for studying protein biomarkers of
age‐related neurodegenerative diseases. Before characterizing biomarkers unique to each …