Mass spectrometry based targeted protein quantification: methods and applications
S Pan, R Aebersold, R Chen, J Rush… - Journal of proteome …, 2009 - ACS Publications
The recent advance in technology for mass spectrometry-based targeted protein
quantification has opened new avenues for a broad range of proteomic applications in …
quantification has opened new avenues for a broad range of proteomic applications in …
Biomarkers for Alzheimer's disease and other forms of dementia: clinical needs, limitations and future aspects
A Cedazo-Minguez, B Winblad - Experimental gerontology, 2010 - Elsevier
An early diagnosis of Alzheimer's disease (AD) and other types of dementia-causing
disorders is vital in order to achieve effective treatments. Fortunately, in the recent years the …
disorders is vital in order to achieve effective treatments. Fortunately, in the recent years the …
Proteomics of human cerebrospinal fluid: discovery and verification of biomarker candidates in neurodegenerative diseases using quantitative proteomics
There is an urgent need for novel biomarkers that can be used to improve the diagnosis,
predict the disease progression, improve our understanding of the pathology or serve as …
predict the disease progression, improve our understanding of the pathology or serve as …
[HTML][HTML] Bilingualism and cognitive reserve: a critical overview and a plea for methodological innovations
The decline of cognitive skills throughout healthy or pathological aging can be slowed down
by experiences which foster cognitive reserve (CR). Recently, some studies on Alzheimer's …
by experiences which foster cognitive reserve (CR). Recently, some studies on Alzheimer's …
Neuronal pentraxin receptor in cerebrospinal fluid as a potential biomarker for neurodegenerative diseases
Neurodegenerative diseases, such as Alzheimer's disease (AD) and Parkinson's disease
(PD), are characterized by progressive loss of cognitive function, dementia, and problems …
(PD), are characterized by progressive loss of cognitive function, dementia, and problems …
Diffusion-MRI in neurodegenerative disorders
J Goveas, L O'Dwyer, M Mascalchi, M Cosottini… - Magnetic resonance …, 2015 - Elsevier
The ability to image the whole brain through ever more subtle and specific
methods/contrasts has come to play a key role in understanding the basis of brain …
methods/contrasts has come to play a key role in understanding the basis of brain …
Biomarker discovery in neurodegenerative diseases: a proteomic approach
Biomarkers for neurodegenerative disorders are essential to facilitate disease diagnosis,
ideally at early stages, monitor disease progression, and assess response to existing and …
ideally at early stages, monitor disease progression, and assess response to existing and …
The effect of preanalytical factors on stability of the proteome and selected metabolites in cerebrospinal fluid (CSF)
T Rosenling, CL Slim, C Christin, L Coulier… - Journal of proteome …, 2009 - ACS Publications
To standardize the use of cerebrospinal fluid (CSF) for biomarker research, a set of stability
studies have been performed on porcine samples to investigate the influence of common …
studies have been performed on porcine samples to investigate the influence of common …
[HTML][HTML] MS-based glycomics: An analytical tool to assess nervous system diseases
Neurological diseases affect millions of peopleochemistryorldwide and are continuously
increasing due to the globe's aging population. Such diseases affect the nervous system …
increasing due to the globe's aging population. Such diseases affect the nervous system …
A combined dataset of human cerebrospinal fluid proteins identified by multi‐dimensional chromatography and tandem mass spectrometry
S Pan, D Zhu, JF Quinn, ER Peskind, TJ Montine… - …, 2007 - Wiley Online Library
Human cerebrospinal fluid (CSF) is an important source for studying protein biomarkers of
age‐related neurodegenerative diseases. Before characterizing biomarkers unique to each …
age‐related neurodegenerative diseases. Before characterizing biomarkers unique to each …