Background Missing data are common in medical research, which can lead to a loss in
statistical power and potentially biased results if not handled appropriately. Multiple …

Children differ from adults in many aspects of pharmacotherapy, including capabilities for
drug administration, medicine-related toxicity, and taste preferences. It is essential that …

Plasmodium falciparum resistance to chloroquine and sulphadoxine–pyrimethamine has led
to the recent adoption of artemisinin-based combination therapies (ACTs) as the first line of …

This article gives an overview of some of the ongoing challenges that are faced in the
prevention, diagnosis and treatment of malaria. Malaria causes approximately 881,000 …

With the elimination of malaria now considered a realistic goal, it would be useful for
scientists and policy makers to have an inventory of the arsenal of antimalarials, current and …

Artemisinin combination therapies (ACTs) have been used as the first‐line treatments
against Plasmodium falciparum malaria for decades. Recent advances in chemical …

As drug-resistant falciparum malaria has continued to evolve and spread worldwide,
artemisinin-based combination therapies (ACT) have become the centerpiece of global …

Malaria is one of the most significant causes of morbidity and mortality worldwide. Every
year, nearly one million deaths result from malaria infection. Malaria can be controlled in …

Introduction: Chemotherapy of malaria has become a rapidly changing field. Less than two
decades ago, treatment regimens were increasingly bound to fail due to emerging drug …

Background There is a need for new artemisinin-based combination therapies that are
convenient, effective, and safe. We compared the efficacy and safety of pyronaridine …