Early-frame [18F] florbetaben PET/MRI for cerebral blood flow quantification in patients with cognitive impairment: comparison to an [15O] water gold standard

A Fettahoglu, M Zhao, M Khalighi… - Journal of Nuclear …, 2024 - Soc Nuclear Med
Cerebral blood flow (CBF) may be estimated from early-frame PET imaging of lipophilic
tracers, such as amyloid agents, enabling measurement of this important biomarker in …

Tau pathology as determinant of changes in atrophy and cerebral blood flow: a multi-modal longitudinal imaging study

D Visser, SCJ Verfaillie, I Bosch, I Brouwer… - European journal of …, 2023 - Springer
Purpose Tau pathology is associated with concurrent atrophy and decreased cerebral blood
flow (CBF) in Alzheimer's disease (AD), but less is known about their temporal relationships …

Head-to-head comparison of relative cerebral blood flow derived from dynamic [18F]florbetapir and [18F]flortaucipir PET in subjects with subjective cognitive decline

H Tuncel, D Visser, T Timmers, EE Wolters… - EJNMMI research, 2023 - Springer
Background Dynamic PET imaging studies provide accurate estimates of specific binding,
but also measure the relative tracer delivery (R1), which is a proxy for relative cerebral blood …

The Early Perfusion Image Is Useful to Support the Visual Interpretation of Brain Amyloid-PET With 18F-Flutemetamol in Borderline Cases

FL Mathies, F Heeman, PJ Visser… - Clinical Nuclear …, 2024 - journals.lww.com
Purpose Visual interpretation of brain amyloid-β (Aβ) PET can be difficult in individuals with
borderline Aβ burden. Coregistration with individual MRI is recommended in these cases …