Apparent changes in the epidemiology and severity of multiple sclerosis

N Koch-Henriksen, M Magyari - Nature Reviews Neurology, 2021 - nature.com
Multiple sclerosis (MS) is an immunological disease that causes acute inflammatory lesions
and chronic inflammation in the CNS, leading to tissue damage and disability. As awareness …

Environmental risk factors and multiple sclerosis: an umbrella review of systematic reviews and meta-analyses

L Belbasis, V Bellou, E Evangelou… - The Lancet …, 2015 - thelancet.com
Background The cause of multiple sclerosis is believed to involve environmental exposure
and genetic susceptibility. We aimed to summarise the environmental risk factors that have …

Blood–brain barrier disruption and enhanced vascular permeability in the multiple sclerosis model EAE

J Bennett, J Basivireddy, A Kollar, KE Biron… - Journal of …, 2010 - Elsevier
Multiple sclerosis (MS) is a demyelinating disease characterized by the breakdown of the
blood–brain barrier (BBB), and accumulation of inflammatory infiltrates in the central …

Vascular aspects of multiple sclerosis

M D'haeseleer, M Cambron, L Vanopdenbosch… - The Lancet …, 2011 - thelancet.com
Three types of vascular dysfunction have been described in multiple sclerosis (MS). First,
findings from epidemiological studies suggest that patients with MS have a higher risk for …

No cerebrocervical venous congestion in patients with multiple sclerosis

F Doepp, F Paul, JM Valdueza, K Schmierer… - Annals of …, 2010 - Wiley Online Library
Objective: Multiple sclerosis (MS) is characterized by demyelination centered around
cerebral veins. Recent studies suggested this topographic pattern may be caused by venous …

Prevalence, sensitivity, and specificity of chronic cerebrospinal venous insufficiency in MS

R Zivadinov, K Marr, G Cutter, M Ramanathan… - Neurology, 2011 - AAN Enterprises
Background: Chronic cerebrospinal venous insufficiency (CCSVI) was recently described in
patients with multiple sclerosis (MS). A subject is considered CCSVI positive if≥ 2 venous …

Venous and cerebrospinal fluid flow in multiple sclerosis: a case‐control study

P Sundström, A Wåhlin, K Ambarki… - Annals of …, 2010 - Wiley Online Library
The prevailing view on multiple sclerosis etiopathogenesis has been challenged by the
suggested new entity chronic cerebrospinal venous insufficiency. To test this hypothesis, we …

Temporal trends in multiple sclerosis prevalence and incidence in a large population

DL Rotstein, H Chen, AS Wilton, JC Kwong, RA Marrie… - Neurology, 2018 - AAN Enterprises
Objective We sought to better understand the reasons for increasing prevalence of multiple
sclerosis (MS) by studying prevalence in relation to incidence, mortality rates, sex ratio, and …

Eagle's syndrome: embryology, anatomy, and clinical management

DJ Fusco, S Asteraki, RF Spetzler - Acta neurochirurgica, 2012 - Springer
Background Eagle's syndrome refers to a rare constellation of neuropathic and vascular
occlusive symptoms caused by pathologic elongation or angulation of the styloid process …

[HTML][HTML] Venous hemodynamics in neurological disorders: an analytical review with hydrodynamic analysis

CB Beggs - BMC medicine, 2013 - Springer
Venous abnormalities contribute to the pathophysiology of several neurological conditions.
This paper reviews the literature regarding venous abnormalities in multiple sclerosis (MS) …