A review on nitrates' health benefits and disease prevention

M Apte, N Nadavade, SS Sheikh - Nitric Oxide, 2024 - Elsevier
Abstract Dietary nitrates (NO3-) are naturally occurring compounds in various vegetables,
especially beetroot, which is mainly supplemented in the form of BRJ. Dietary nitrates (NO3-) …

Neuronal nitric oxide synthase and post-translational modifications in the development of central nervous system diseases: Implications and regulation

C Maccallini, R Amoroso - Molecules, 2023 - mdpi.com
In the Central Nervous System (CNS), Nitric Oxide (NO) is mainly biosynthesized by
neuronal Nitric Oxide Synthase (nNOS). The dysregulated activation of nNOS in neurons is …

Mutations associated with autism lead to similar synaptic and behavioral alterations in both sexes of male and female mouse brain

MK Tripathi, SK Ojha, M Kartawy, I Khaliulin… - Scientific Reports, 2024 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder based on synaptic
abnormalities. The estimated prevalence rate of male individuals diagnosed with ASD …

Nitric Oxide Synthase Inhibition Prevents Cell Proliferation in Glioblastoma

D Kruglyakov, SK Ojha, M Kartawy, MK Tripathi… - Journal of Molecular …, 2023 - Springer
Glioblastoma multiforme (GBM) is a prevalent and aggressive primary brain tumor,
presenting substantial treatment challenges and high relapse rates. GBM is characterized by …

Effects of extended-release 7-nitroindazole gel formulation treatment on the behavior of Shank3 mouse model of autism

M Abdel-Haq, SK Ojha, W Hamoudi, A Kumar… - Nitric Oxide, 2023 - Elsevier
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by
behavioral deficits such as abnormalities in communication, social interaction, anxiety, and …

Autism Spectrum Disorder: Brain Areas Involved, Neurobiological Mechanisms, Diagnoses and Therapies

J Lamanna, J Meldolesi - International Journal of Molecular Sciences, 2024 - mdpi.com
Autism spectrum disorder (ASD), affecting over 2% of the pre-school children population,
includes an important fraction of the conditions accounting for the heterogeneity of autism …

Nitrosative Stress in Autism: Supportive Evidence and Implications for Mitochondrial Dysfunction

RE Frye, S Rose, I Voinsky, D Gurwitz - Advanced Science, 2024 - Wiley Online Library
A recent study by the Amal team published in this journal in May 2023 proved for the first
time the link of nitric oxide (NO) with autism spectrum disorder (ASD), thereby opening new …

Nitric oxide protects intestinal mucosal barrier function and prevents acute graft rejection after intestinal transplantation: a mini-review

GJ Dugbartey, D Nanteer, I Osae - Nitric Oxide, 2024 - Elsevier
Intestinal transplantation is a complex technical procedure that provides patients suffering
from end-stage intestinal failure an opportunity to enjoy improved quality of life, nutrition and …

Autistic-like behaviour and changes in thalamic cell numbers a rat model of valproic acid-induced autism; A behavioural and stereological study

E Horata, H Ay, D Aslan - Brain Research, 2024 - Elsevier
The contribution of the thalamus to the development and behavioural changes in autism
spectrum disorders (ASD), a neurodevelopmental syndrome, remains unclear. The aim of …

Are salivary NO2−/NO2− and NO3− levels biomarkers for dental caries in children? Systematic review and meta-analysis

B Diaz-Fabregat, W Ramirez-Carmona, ML Cannon… - Nitric Oxide, 2024 - Elsevier
The literature is conflicting regarding salivary nitrite (NO 2−)/nitrite and nitrate (NO 2− and
NO 3−) levels in children affected by dental caries. For this reason, a systematic review to …