Small-cell lung cancer (SCLC) represents about 15% of all lung cancers and is marked by
an exceptionally high proliferative rate, strong predilection for early metastasis and poor …

In the past decade, the introduction of molecularly targeted agents and immune-checkpoint
inhibitors has led to improved survival outcomes for patients with advanced-stage lung …

Background Neoadjuvant or adjuvant immunotherapy can improve outcomes in patients
with resectable non–small-cell lung cancer (NSCLC). Perioperative regimens may combine …

Lung cancer is the leading cause of mortality and person-years of life lost from cancer
among US men and women. Early detection has been shown to be associated with reduced …

Non-invasive approaches for cell-free DNA (cfDNA) assessment provide an opportunity for
cancer detection and intervention. Here, we use a machine learning model for detecting …

Background Lung cancer is made up of distinct subtypes, including non–small-cell lung
cancer (NSCLC) and small-cell lung cancer (SCLC). Although overall mortality from lung …

Somatic mutations are a hallmark of tumorigenesis and may be useful for non-invasive
diagnosis of cancer. We analyzed whole-genome sequencing data from 2,511 individuals in …

With an estimated 160,000 deaths in 2018, lung cancer is the most common cause of cancer
death in the United States. Lung cancer screening using low-dose computed tomography …

The Global Initiative for Chronic Obstructive Lung Disease (GOLD) has published the
complete 2023 GOLD report, which can be freely downloaded from its web page (www …

PURPOSE Low-dose computed tomography (LDCT) for lung cancer screening is effective,
although most eligible people are not being screened. Tools that provide personalized …