SARS-CoV-2 evolution in the Omicron era

C Roemer, DJ Sheward, R Hisner, F Gueli… - Nature …, 2023 - nature.com
Abstract Since SARS-CoV-2 BA. 5 (Omicron) emerged and spread in 2022, Omicron
lineages have markedly diversified. Here we review the evolutionary trajectories and …

Wastewater-based surveillance as a tool for public health action: SARS-CoV-2 and beyond

MD Parkins, BE Lee, N Acosta, M Bautista… - Clinical Microbiology …, 2024 - Am Soc Microbiol
Wastewater-based surveillance (WBS) has undergone dramatic advancement in the context
of the coronavirus disease 2019 (COVID-19) pandemic. The power and potential of this …

[HTML][HTML] Repeated Omicron exposures override ancestral SARS-CoV-2 immune imprinting

A Yisimayi, W Song, J Wang, F Jian, Y Yu, X Chen… - Nature, 2024 - nature.com
The continuing emergence of SARS-CoV-2 variants highlights the need to update COVID-19
vaccine compositions. However, immune imprinting induced by vaccination based on the …

[HTML][HTML] A molnupiravir-associated mutational signature in global SARS-CoV-2 genomes

T Sanderson, R Hisner, I Donovan-Banfield, H Hartman… - Nature, 2023 - nature.com
Molnupiravir, an antiviral medication widely used against severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), acts by inducing mutations in the virus genome during …

XBB. 1.5 monovalent mRNA vaccine booster elicits robust neutralizing antibodies against XBB subvariants and JN. 1

Q Wang, Y Guo, A Bowen, IA Mellis, R Valdez… - Cell Host & Microbe, 2024 - cell.com
COVID-19 vaccines have recently been updated to specifically encode or contain the spike
protein of the SARS-CoV-2 XBB. 1.5 subvariant, but their immunogenicity in humans has yet …

[HTML][HTML] Swift and extensive Omicron outbreak in China after sudden exit from 'zero-COVID'policy

EE Goldberg, Q Lin, EO Romero-Severson… - Nature …, 2023 - nature.com
In late 2022, China transitioned from a strict 'zero-COVID'policy to rapidly abandoning nearly
all interventions and data reporting. This raised great concern about the presumably-rapid …

[HTML][HTML] Rapid assembly of SARS-CoV-2 genomes reveals attenuation of the Omicron BA. 1 variant through NSP6

TY Taha, IP Chen, JM Hayashi, T Tabata… - Nature …, 2023 - nature.com
Abstract Although the SARS-CoV-2 Omicron variant (BA. 1) spread rapidly across the world
and effectively evaded immune responses, its viral fitness in cell and animal models was …

The emergence and evolution of SARS-CoV-2

EC Holmes - Annual Review of Virology, 2024 - annualreviews.org
The origin of SARS-CoV-2 has evoked heated debate and strong accusations, yet
seemingly little resolution. I review the scientific evidence on the origin of SARS-CoV-2 and …

[HTML][HTML] The evolutionary drivers and correlates of viral host jumps

CCS Tan, L van Dorp, F Balloux - Nature Ecology & Evolution, 2024 - nature.com
Most emerging and re-emerging infectious diseases stem from viruses that naturally
circulate in non-human vertebrates. When these viruses cross over into humans, they can …

[HTML][HTML] a rapid global increase in COVID-19 is due to the emergence of the EG. 5 (Eris) subvariant of omicron SARS-CoV-2

DV Parums - … Science Monitor: International Medical Journal of …, 2023 - ncbi.nlm.nih.gov
A new variant of SARS-CoV-2 has currently achieved global domination. EG. 5 (Eris) was
first reported by the World Health Organization (WHO) on February 17, 2023, and …