Automated chemical oligosaccharide synthesis: novel approach to traditional challenges

M Panza, SG Pistorio, KJ Stine… - Chemical reviews, 2018 - ACS Publications
Advances in carbohydrate chemistry have certainly made common oligosaccharides much
more accessible. However, many current methods still rely heavily upon specialized …

Masquerading microbial pathogens: capsular polysaccharides mimic host-tissue molecules

BF Cress, JA Englaender, W He… - FEMS microbiology …, 2014 - academic.oup.com
The increasing prevalence of antibiotic-resistant bacteria portends an impending
postantibiotic age, characterized by diminishing efficacy of common antibiotics and routine …

Recent advances in the production of recombinant glycoconjugate vaccines

E Kay, J Cuccui, BW Wren - npj Vaccines, 2019 - nature.com
Glycoconjugate vaccines against bacteria are one of the success stories of modern
medicine and have led to a significant reduction in the global occurrence of bacterial …

1, 2-cis O-Glycosylation: methods, strategies, principles

AV Demchenko - Current organic chemistry, 2003 - ingentaconnect.com
The aim of this review is to discuss the accomplishments made in the area of the
stereoselective formation of a 1, 2-cis glycosidic bond. Importance of this subject derives …

Immunotherapy for cancer: synthetic carbohydrate-based vaccines

T Buskas, P Thompson, GJ Boons - Chemical Communications, 2009 - pubs.rsc.org
Aberrant glycosylation of glycoproteins and glycolipids of cancer cells, which correlates with
poor survival rates, is being exploited for the development of immunotherapies for cancer. In …

A Photoflow Reactor for the Continuous Photoredox‐Mediated Synthesis of C‐Glycoamino Acids and C‐Glycolipids

RS Andrews, JJ Becker, MR Gagné - Angewandte Chemie, 2012 - infona.pl
Photochemie im Fluss: Durch den Einsatz stark absorbierender [RuL 3] 2+‐
Photosensibilisatoren in einem einfachen Flussreaktor gelingen Photoredoxreaktionen …

Synthesis and application of carbohydrate-containing polymers

Q Wang, JS Dordick, RJ Linhardt - Chemistry of materials, 2002 - ACS Publications
Polysaccharides and glycoproteins participate in a number of biochemical reactions and
cell− cell recognition processes in vivo. Synthetic carbohydrate-based polymers are being …

Glycopeptides as versatile tools for glycobiology

T Buskas, S Ingale, GJ Boons - Glycobiology, 2006 - academic.oup.com
This review describes the recent advances in the field of glycopeptide and small
glycoprotein synthesis. The strategies covered include chemical and chemoenzymatic …

A possible oligosaccharide-conjugate vaccine candidate for Clostridium difficile is antigenic and immunogenic

MA Oberli, ML Hecht, P Bindschädler, A Adibekian… - Chemistry & Biology, 2011 - cell.com
Nosocomial infections with the Gram-positive pathogen Clostridium difficile pose a major
risk for hospitalized patients and result in significant costs to health care systems. Here, we …

Preparation of multifunctional glyconanoparticles as a platform for potential carbohydrate-based anticancer vaccines

R Ojeda, JL de Paz, AG Barrientos… - Carbohydrate …, 2007 - Elsevier
A novel platform for anticancer vaccines has been prepared using glyconanotechnology
recently developed in our laboratory. Ten different multifunctional gold glyconanoparticles …