Galcanezumab effect on “whole pain burden” and multidimensional outcomes in migraine patients with previous unsuccessful treatments: a real-world experience

M Silvestro, A Tessitore, I Orologio, R De Micco… - The Journal of …, 2022 - Springer
Background Clinical trials have demonstrated galcanezumab as safe and effective in
migraine prevention. However, real-life data are still lacking and overlook the impact of …

Efficacy and safety of monoclonal antibody against calcitonin gene-related peptide or its receptor for migraine patients with prior preventive treatment failure: a network …

X Wang, D Wen, Q He, C You, L Ma - The Journal of Headache and Pain, 2022 - Springer
Objective The relative effects of monoclonal antibody against calcitonin gene-related
peptide (CGRP) or its receptor for adult migraine patients with prior treatment failure remains …

Real-world evidence of galcanezumab for migraine treatment in Japan: a retrospective analysis

T Takizawa, S Ohtani, N Watanabe, N Miyazaki… - BMC neurology, 2022 - Springer
Objective To evaluate the efficacy and safety of galcanezumab in patients with migraine in a
real-world setting in Japan. Background Galcanezumab is the first anti-calcitonin gene …

Safety and efficacy of erenumab in patients with trigeminal neuralgia in Denmark: a double-blind, randomised, placebo-controlled, proof-of-concept study

ASS Andersen, S Maarbjerg, N Noory… - The Lancet …, 2022 - thelancet.com
Background Trigeminal neuralgia is a severe facial pain disorder that is difficult to treat.
Erenumab, a monoclonal antibody against the calcitonin gene-related peptide (CGRP) …

Management of medication overuse (MO) and medication overuse headache (MOH) S1 guideline

HC Diener, P Kropp, T Dresler, S Evers… - … research and practice, 2022 - Springer
Introduction Chronic headache due to the overuse of medication for the treatment of
migraine attacks has a prevalence of 0.5–2.0%. This guideline provides guidance for the …

Resistant and refractory migraine: clinical presentation, pathophysiology, and management

R Ornello, AP Andreou, E De Matteis, TP Jürgens… - …, 2024 - thelancet.com
Migraine is a leading cause of disability worldwide. A minority of individuals with migraine
develop resistant or refractory conditions characterised by≥ 8 monthly days of debilitating …

Methodological considerations on real-world evidence studies of monoclonal antibodies against the CGRP-pathway for migraine: a systematic review

N Vandenbussche, K Pisarek, K Paemeleire - The Journal of Headache …, 2023 - Springer
Background Real-world data are accumulating on the effectiveness, tolerability and safety of
anti-calcitonin gene-related peptide pathway monoclonal antibodies for the preventive …

[HTML][HTML] The arrival of anti-CGRP monoclonal antibodies in migraine

F Cohen, H Yuan, EMG DePoy, SD Silberstein - Neurotherapeutics, 2022 - Elsevier
Remarkable advancements have been made in the field of migraine pathophysiology and
pharmacotherapy over the past decade. Understanding the molecular mechanism of …

Serum CGRP in migraine patients using erenumab as preventive treatment

S de Vries Lentsch, IM Garrelds, AHJ Danser… - The Journal of …, 2022 - Springer
Abstract Aim Serum levels of Calcitonin Gene-Related Peptide (CGRP)-like
immunoreactivity (CGRP-LI) in migraine patients before and after starting treatment with …

Calcitonin gene‐related peptide‐targeting therapies are a first‐line option for the prevention of migraine: An American Headache Society position statement update

AC Charles, KB Digre, PJ Goadsby… - … : The Journal of …, 2024 - Wiley Online Library
Objective To provide a position statement update from The American Headache Society
specifically regarding therapies targeting calcitonin gene‐related peptide (CGRP) for the …