Unmet needs in preventive treatment of migraine
Migraine represents the most common cause of work disability in young women and the
second one in the general population. Preventive treatment can reduce the frequency of …
second one in the general population. Preventive treatment can reduce the frequency of …
Changes in migraine interictal burden following treatment with galcanezumab: Results from a phase III randomized, placebo‐controlled study
Objective To evaluate changes in interictal burden with galcanezumab versus placebo in
patients with episodic (EM) or chronic migraine (CM). Background The disruptive effects of …
patients with episodic (EM) or chronic migraine (CM). Background The disruptive effects of …
Emerging drugs for the preventive treatment of migraine: a review of CGRP monoclonal antibodies and gepants trials
M Silvestro, I Orologio, M Siciliano, F Trojsi… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Migraine is a leading cause of years lived with disability and preventive
strategies represent a mainstay to reduce health-related disability and improve quality of life …
strategies represent a mainstay to reduce health-related disability and improve quality of life …
One-year prospective real-world assessment of effectiveness and safety of erenumab in migraine prevention: results of the French FHU INOVPAIN registry study
M Lanteri-Minet, R Fabre, C Martin, K Pradat… - The Journal of …, 2023 - Springer
Background Randomized clinical trials have demonstrated efficacy and safety of erenumab.
The aim of this study is to evaluate the effectiveness and safety of erenumab in a real-world …
The aim of this study is to evaluate the effectiveness and safety of erenumab in a real-world …
Efficacy and safety of eptinezumab for migraine prevention in patients with prior preventive treatment failures: subgroup analysis of the randomized, placebo …
M Ashina, M Lanteri-Minet, A Ettrup… - …, 2023 - journals.sagepub.com
Background Migraine is a disabling neurological disease adversely affecting many aspects
of life. Most patients are still required to have failed several older oral preventive therapies …
of life. Most patients are still required to have failed several older oral preventive therapies …
Pharmacologic prevention of migraine
V Tzankova, WJ Becker, TLH Chan - Cmaj, 2023 - Can Med Assoc
• Oral medications traditionally used for the prevention of migraine and known to be effective
include anti-epileptic, β-blocker, antihypertensive and antidepressant drugs.• …
include anti-epileptic, β-blocker, antihypertensive and antidepressant drugs.• …
Long-term effectiveness and tolerability of galcanezumab in patients with migraine excluded from clinical trials: real world evidence of 1055 patients with 1 year follow …
V Obach, F Velasco, R Alvarez Escudero… - The Journal of …, 2023 - Springer
Background Galcanezumab has shown efficacy and effectiveness in the treatment of
episodic and chronic migraine (CM), however, the population represented in randomized …
episodic and chronic migraine (CM), however, the population represented in randomized …
Adverse event reporting of four anti-Calcitonin gene-related peptide monoclonal antibodies for migraine prevention: a real-world study based on the FDA adverse …
W Sun, Y Li, B Xia, J Chen, Y Liu, J Pang… - Frontiers in …, 2024 - frontiersin.org
Background: Anti-Calcitonin gene-related peptide monoclonal antibodies (anti-CGRP mAbs)
have shown significant efficacy in preventing migraine. However, there have been limited …
have shown significant efficacy in preventing migraine. However, there have been limited …
Real-world experience with calcitonin gene-related peptide-targeted antibodies for migraine prevention: a retrospective observational cohort study at two Japanese …
M Shibata, K Fujita, E Hoshino, K Minami, K Koizumi… - BMC neurology, 2024 - Springer
Background Although randomized controlled trials (RCTs) have shown that calcitonin gene-
related peptide (CGRP)-targeted monoclonal antibodies (CGRP mAbs) are an efficacious …
related peptide (CGRP)-targeted monoclonal antibodies (CGRP mAbs) are an efficacious …
Long-term effectiveness of eptinezumab in patients with migraine and prior preventive treatment failures: extension of a randomized controlled trial
Background Eptinezumab demonstrated efficacy in adults with migraine and prior preventive
treatment failures in the placebo-controlled phase of the DELIVER clinical trial; its long-term …
treatment failures in the placebo-controlled phase of the DELIVER clinical trial; its long-term …