Gastroprotective potential of red onion (Allium cepa L.) peel in ethanol-induced gastric injury in rats: involvement of Nrf2/HO-1 and HMGB-1/NF-κB trajectories

NB Ali, SSA Ibrahim, MA Alsherbiny, E Sheta… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance The utilization of plants with therapeutic properties in
traditional medicine has a longstanding practice. Among them, the well-known Allium cepa …

Treatment of gastric ulcer, traditional Chinese medicine may be a better choice

H Gong, N Zhao, C Zhu, L Luo, S Liu - Journal of Ethnopharmacology, 2024 - Elsevier
Ethnopharmacological relevance Gastric ulcer (GU) is the injury of the gastric mucosa
caused by the stimulation of various pathogenic factors penetrating the deep mucosal …

[HTML][HTML] Gastroprotective effects of Polygonatum odoratum in rodents by regulation of apoptotic proteins and inflammatory cytokines

AA Mariod, AAJ Jabbar, ZZ Alamri, AS Al Rashdi… - Saudi Journal of …, 2023 - Elsevier
In an increasing interest in natural antiulcer compounds that may have gastric healing
effects and possibly prevent ulcer recurrence, Polygonatum odoratum appears as a strong …

Validation of an HPLC-DAD Method for quercetin quantification in nanoparticles

D Carvalho, Â Jesus, C Pinho, RF Oliveira, F Moreira… - Pharmaceuticals, 2023 - mdpi.com
The evaluation of the efficacy of incorporation of quercetin in nanoparticles is crucial, both
for the development and quality control of pharmaceutical formulations. The validation of …

[HTML][HTML] Enhancing the bioavailability and gut health benefits of quercetin from sprouted onions: A comprehensive review in the context of food-derived bioactives

I Majid, D Majid, HA Makroo, BN Dar - Food Chemistry Advances, 2024 - Elsevier
To optimize food-derived bioactive components, a significant concern is their stability and
bioavailability. Quercetin, a well-known polyphenol found in onions, has garnered attention …

Ipomoea carnea mitigates ethanol-induced ulcers in irradiated rats via Nrf2/HO−1 pathway: an in vivo and in silico study

MA Ghareeb, HS Mohammed, T Aboushousha… - Scientific Reports, 2024 - nature.com
The aim of this study was to investigate the potential of Ipomoea carnea flower methanolic
extract (ICME) as a natural gastroprotective therapy against ethanol-induced gastric ulcers …

Repeated 28-Day Oral Toxicological Study and Gastroprotective Effects of Nigella sativa L. Oil (Shuhada) against Ethanol-Induced Gastric Mucosal Injury in Rats

S Sanpinit, P Wetchakul, P Chonsut, N Ngamdokmai… - Nutrients, 2023 - mdpi.com
Nigella sativa L. and black seeds are traditionally used for cooking and medicinal purposes
in Arab and other countries. Although N. sativa seed extract has many known biological …

The gastroprotective effect of Yucca filamentosa standardized crude leaves extract versus its nano-cubosomal formulation in ethanol-induced gastric injury

SSA Ibrahim, SM Bassam, S El-Hawary, E Sheta… - International …, 2024 - Elsevier
Yucca filamentosa (YF) is widely used in folk medicine for its anti-inflammatory effects. Our
study aimed to evaluate the chemical profile of YF extracts. Additionally, the gastroprotective …

Ferulic acid nanoemulsion as a promising anti-ulcer tool: in vitro and in vivo assessment

H Abd-Allah, GA Abdel Jaleel, A Hassan… - Drug Development …, 2024 - Taylor & Francis
Objective Ferulic acid (FA) is a promising nutraceutical molecule which exhibits antioxidant
and anti-inflammatory properties, but it suffers from poor solubility and bioavailability. In the …

The development of expandable films based on starch and chitosan for stomach-specific delivery of quercetin solid dispersions

R Wiwattanapatapee, T Yaoduang, M Bairaham… - Journal of Drug Delivery …, 2024 - Elsevier
Expandable films for stomach-specific delivery were developed to release quercetin, a
flavonoid with in vivo gastroprotective effects, in a prolonged release fashion. We found that …