Due to their biotechnological relevance as well as their importance as disease agents,
filamentous fungi and oomycetes have been prime candidates for genetic selection and in …

Filamentous fungi are widely used in biotechnology as cell factories for the production of
chemicals, pharmaceuticals and enzymes. In order to improve their productivities, genetic …

Cryptococcus neoformans is an opportunistic fungal pathogen that causes cryptococcal
meningoencephalitis, particularly in immunocompromised patients. The fungal cell wall is an …

The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

ABSTRACT A high frequency of nonhomologous recombination has hampered gene
targeting approaches in the model apicomplexan parasite Toxoplasma gondii. To address …

Gene targeting frequencies in Aspergillus niger are often very low and hamper efficient
functional genomics in this biotechnologically important fungus. Deletion of the A. niger kusA …

Filamentous fungi have a long-standing tradition as industrial producers of primary and
secondary metabolites. Initially, industrial scientists selected production strains from natural …

Cryptococcus neoformans is a fungal pathogen that claims hundreds of thousands of lives
annually. Targeted genetic manipulation through biolistic transformation in C. neoformans …

The filamentous fungus Aspergillus niger is one of the main contaminants of the
International Space Station (ISS). It forms highly pigmented, airborne spores that have thick …

Cryptococcus neoformans is a prevalent human fungal pathogen that must survive within
various tissues in order to establish a human infection. We have identified the C …