[HTML][HTML] Recent Advances in 64Cu/67Cu-Based Radiopharmaceuticals

OO Krasnovskaya, D Abramchuck, A Erofeev… - International Journal of …, 2023 - mdpi.com
Copper-64 (T1/2= 12.7 h) is a positron and beta-emitting isotope, with decay characteristics
suitable for both positron emission tomography (PET) imaging and radiotherapy of cancer …

[HTML][HTML] Transition metal ions and neurotransmitters: coordination chemistry and implications for neurodegeneration

J Yoo, J Han, MH Lim - RSC Chemical Biology, 2023 - pubs.rsc.org
Neurodegeneration is characterized by a disturbance in neurotransmitter-mediated
signaling pathways. Recent studies have highlighted the significant role of transition metal …

[HTML][HTML] Hyperglucagonaemia in diabetes: altered amino acid metabolism triggers mTORC1 activation, which drives glucagon production

Y Riahi, A Kogot-Levin, L Kadosh, B Agranovich… - Diabetologia, 2023 - Springer
Aim/hypothesis Hyperglycaemia is associated with alpha cell dysfunction, leading to
dysregulated glucagon secretion in type 1 and type 2 diabetes; however, the mechanisms …

[HTML][HTML] Peptide Therapeutics: Unveiling the Potential against Cancer—A Journey through 1989

O Al Musaimi - Cancers, 2024 - mdpi.com
Simple Summary The extraordinary growth in the global pharmaceutical industry has
extended to include peptides, which are amino acids linked together with an amide bond …

[HTML][HTML] Tumour heterogeneity and the consequent practical challenges in the management of gastroenteropancreatic neuroendocrine neoplasms

I Reccia, M Pai, J Kumar, D Spalding, A Frilling - Cancers, 2023 - mdpi.com
Tumour heterogeneity is a common phenomenon in neuroendocrine neoplasms (NENs)
and a significant cause of treatment failure and disease progression. Genetic and epigenetic …

[HTML][HTML] Models in pancreatic neuroendocrine neoplasms: Current perspectives and future directions

SD Forsythe, T Pu, SG Andrews, JP Madigan… - Cancers, 2023 - mdpi.com
Simple Summary Pancreatic neuroendocrine neoplasms (pNENs) are a rare and
understudied cancer. Some of this low knowledge base is due to a historical lack of study …

[HTML][HTML] Cuprotosis clusters predict prognosis and immunotherapy response in low-grade glioma

W Zhu, Z Chen, M Fu, Q Li, X Chen, X Li, N Luo… - Apoptosis, 2024 - Springer
Cuprotosis, an emerging mode of cell death, has recently caught the attention of researchers
worldwide. However, its impact on low-grade glioma (LGG) patients has not been fully …

[HTML][HTML] Immunological role and prognostic value of somatostatin receptor family members in colon adenocarcinoma

X Yu, X Yang, H Nie, W Jiang, X He… - Frontiers in Pharmacology, 2023 - frontiersin.org
Colon adenocarcinoma (COAD) is among the most prevalent cancers worldwide, ranking as
the third most prevalent malignancy in incidence and mortality. The somatostatin receptor …

[HTML][HTML] Diabetes management in cancer patients. An Italian association of medical oncology, Italian association of medical Diabetologists, Italian Society of …

N Silvestris, T Franchina, M Gallo, A Argentiero… - ESMO open, 2023 - Elsevier
Highlights•This multidisciplinary consensus position paper focuses on identifying a novel
specialty field,'diabeto-oncology'.•A critical overview of cancer and diabetes co-management …

From biology to clinical practice: antiproliferative effects of somatostatin analogs in neuroendocrine neoplasms

P Melhorn, P Mazal, L Wolff… - Therapeutic …, 2024 - journals.sagepub.com
Somatostatin analogs (SSA), specifically octreotide and lanreotide, have demonstrated
antiproliferative effects in patients with neuroendocrine tumors (NET), a group of rare …