Taste reception
B Lindemann - Physiological reviews, 1996 - journals.physiology.org
Recent research on cellular mechanisms of peripheral taste has defined transduction
pathways involving membrane receptors, G proteins, second messengers, and ion …
pathways involving membrane receptors, G proteins, second messengers, and ion …
Mechanisms of taste transduction
SC Kinnamon, RF Margolskee - Current opinion in neurobiology, 1996 - Elsevier
Taste cells use a wide variety of mechanisms for transduction. Ionic stimuli, such as salts
and acids, interact directly with ion channels to depolarize taste cells. More complex stimuli …
and acids, interact directly with ion channels to depolarize taste cells. More complex stimuli …
[HTML][HTML] T2Rs function as bitter taste receptors
J Chandrashekar, KL Mueller, MA Hoon, E Adler… - Cell, 2000 - cell.com
Bitter taste perception provides animals with critical protection against ingestion of
poisonous compounds. In the accompanying paper, we report the characterization of a large …
poisonous compounds. In the accompanying paper, we report the characterization of a large …
A metabotropic glutamate receptor variant functions as a taste receptor
N Chaudhari, AM Landin, SD Roper - Nature neuroscience, 2000 - nature.com
Sensory transduction for many taste stimuli such as sugars, some bitter compounds and
amino acids is thought to be mediated via G protein-coupled receptors (GPCRs), although …
amino acids is thought to be mediated via G protein-coupled receptors (GPCRs), although …
Molecular cloning and functional expression of a new human CC-chemokine receptor gene
M Samson, O Labbe, C Mollereau, G Vassart… - Biochemistry, 1996 - ACS Publications
The cloning of several receptors activated by either CC or CXC chemokines and belonging
to the G protein-coupled family of receptors has been reported recently. In the present work …
to the G protein-coupled family of receptors has been reported recently. In the present work …
Gγ13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium
L Huang, YG Shanker, J Dubauskaite, JZ Zheng… - Nature …, 1999 - nature.com
Gustducin is a transducin-like G protein selectively expressed in taste receptor cells. The α
subunit of gustducin (α-gustducin) is critical for transduction of responses to bitter or sweet …
subunit of gustducin (α-gustducin) is critical for transduction of responses to bitter or sweet …
The taste of monosodium glutamate: membrane receptors in taste buds
N Chaudhari, H Yang, C Lamp, E Delay… - Journal of …, 1996 - Soc Neuroscience
Receptor proteins for photoreception have been studied for several decades. More recently,
putative receptors for olfaction have been isolated and characterized. In contrast, no …
putative receptors for olfaction have been isolated and characterized. In contrast, no …
Coupling of bitter receptor to phosphodiesterase through transducin in taste receptor cells
L Ruiz-Avila, SK McLaughlin, D Wildman, PJ McKinnon… - Nature, 1995 - nature.com
THE rod and cone transducing are specific G proteins originally thought to be present only in
photoreceptor cells of the vertebrate retina1–4. Transducins convert light stimulation of …
photoreceptor cells of the vertebrate retina1–4. Transducins convert light stimulation of …
A silent chemokine receptor regulates steady-state leukocyte homing in vivo
K Heinzel, C Benz, CC Bleul - Proceedings of the national …, 2007 - National Acad Sciences
The location of leukocytes in different microenvironments is intimately connected to their
function and, in the case of leukocyte precursors, to the executed differentiation and …
function and, in the case of leukocyte precursors, to the executed differentiation and …
Characterization of mouse CCX‐CKR, a receptor for the lymphocyte‐attracting chemokines TECK/mCCL25, SLC/mCCL21 and MIP‐3β/mCCL19: comparison to …
JR Townson, RJB Nibbs - European journal of immunology, 2002 - Wiley Online Library
We report here the identification and characterization of murine CCX‐CKR, a high affinity
receptor for the murine β‐chemokines SLC/mCCL21, MIP‐3β/mCCL19 and TECK/mCCL25 …
receptor for the murine β‐chemokines SLC/mCCL21, MIP‐3β/mCCL19 and TECK/mCCL25 …