Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

Breast cancer is a complex and diverse condition that disrupts multiple signaling pathways
essential for cell proliferation, survival, and differentiation. Recently, the significant …

Chronic obstructive pulmonary disease (COPD) is one of the most common chronic
respiratory diseases with high morbidity and mortality. It has become the fifth most burdened …

Introduction Idiopathic pulmonary fibrosis (IPF) is a progressive fibrosing interstitial lung
disease of unknown aetiology and cure. Recent studies have reported a dysregulation of …

Limited information is available regarding epigenomic events mediating initiation and
progression of tobacco-induced lung cancers. In this study, we established an in vitro system …

N 6-methyladenosine (m 6 A) is the most abundant modification in eukaryotic cells, and it
regulates RNA transcription, processing, splicing, degradation, and translation. Long non …

Liver disease has become a major health problem worldwide due to its high morbidity and
mortality. In recent years, a large body of literature has shown that mesenchymal stem cell …

With completing the whole genome sequencing project, awareness of lncRNA further
deepened. The growth arrest-specific transcript 5 (GAS5) was initially identified in growth …

Exosomes are a type of small endosomal‐derived vesicles ranging from 30 to 150 nm,
which can serve as functional mediators in cell‐to‐cell communication and various …

Background The active metabolite of 5-Fluorouracil (5FU), used in the treatment of several
types of cancer, acts by inhibiting the thymidylate synthase encoded by the TYMS gene …