Ovarian aging in humans: potential strategies for extending reproductive lifespan

MB Cavalcante, OGM Sampaio, FEA Câmara… - Geroscience, 2023 - Springer
Ovarian reserve is a term used to estimate the total number of immature follicles present in
the ovaries. Between birth and menopause, there is a progressive decrease in the number …

Ovarian tissue cryopreservation and transplantation: a review on reactive oxygen species generation and antioxidant therapy

A Najafi, E Asadi, JD Benson - Cell and Tissue Research, 2023 - Springer
Cancer is the leading cause of death worldwide. Fortunately, the survival rate of cancer
continues to rise, owing to advances in cancer treatments. However, these treatments are …

The gut metabolite 3-hydroxyphenylacetic acid rejuvenates spermatogenic dysfunction in aged mice through GPX4-mediated ferroptosis

Z Jin, Y Yang, Y Cao, Q Wen, Y Xi, J Cheng, Q Zhao… - Microbiome, 2023 - Springer
Background Aging-related fertility decline is a prevalent concern globally. Male reproductive
system aging is mainly characterized by a decrease in sperm quality and fertility. While it is …

Genetics of infertility: a paradigm shift for medically assisted reproduction

W Verpoest, Ö Okutman, A Van Der Kelen… - Human …, 2023 - academic.oup.com
The field of reproductive genetics has undergone significant advancements with the
completion of the Human Genome Project and the development of high-throughput …

Impacts of vitrification on the transcriptome of human ovarian tissue in patients with gynecological cancer

R Gu, N Ge, B Huang, J Fu, Y Zhang, N Wang… - Frontiers in …, 2023 - frontiersin.org
Objective: This study investigated the effects of a vitrification/warming procedure on the
mRNA transcriptome of human ovarian tissues. Design: Human ovarian tissues were …

Offline social capital, online social capital, and fertility intentions: evidence from China

J Zhao, Z Zou, J Chen, Y Chen, W Lin, X Pei… - Humanities and Social …, 2024 - nature.com
China has experienced both ultra-low fertility and moderate aging in recent years, both of
which pose serious challenges to the country's development. Previous studies have shown …