Circadian rhythms in neurodegenerative disorders
M Nassan, A Videnovic - Nature Reviews Neurology, 2022 - nature.com
Endogenous biological clocks, orchestrated by the suprachiasmatic nucleus, time the
circadian rhythms that synchronize physiological and behavioural functions in humans. The …
circadian rhythms that synchronize physiological and behavioural functions in humans. The …
'The clocks that time us'—circadian rhythms in neurodegenerative disorders
Circadian rhythms are physiological and behavioural cycles generated by an endogenous
biological clock, the suprachiasmatic nucleus. The circadian system influences the majority …
biological clock, the suprachiasmatic nucleus. The circadian system influences the majority …
Defining circadian disruption in neurodegenerative disorders
CS Colwell - The Journal of clinical investigation, 2021 - Am Soc Clin Investig
Neurodegenerative diseases encompass a large group of conditions that are clinically and
pathologically diverse yet are linked by a shared pathology of misfolded proteins. The …
pathologically diverse yet are linked by a shared pathology of misfolded proteins. The …
[HTML][HTML] High-fat diet-induced memory impairment in triple-transgenic Alzheimer's disease (3xTgAD) mice is independent of changes in amyloid and tau pathology
EM Knight, IVA Martins, S Gümüsgöz, SM Allan… - Neurobiology of …, 2014 - Elsevier
Obesity and consumption of a high-fat diet are known to increase the risk of Alzheimer's
disease (AD). Diets high in fat also increase disease neuropathology and/or cognitive …
disease (AD). Diets high in fat also increase disease neuropathology and/or cognitive …
Metabolic and non-cognitive manifestations of Alzheimer's disease: the hypothalamus as both culprit and target of pathology
M Ishii, C Iadecola - Cell metabolism, 2015 - cell.com
Alzheimer's disease (AD) is increasingly recognized as a complex neurodegenerative
disease beginning decades prior to the cognitive decline. While cognitive deficits remain the …
disease beginning decades prior to the cognitive decline. While cognitive deficits remain the …
The circadian system in Alzheimer's disease: disturbances, mechanisms, and opportunities
AN Coogan, B Schutová, S Husung, K Furczyk… - Biological …, 2013 - Elsevier
Alzheimer's disease (AD) is a devastating neurodegenerative condition associated with
severe cognitive and behavioral impairments. Circadian rhythms are recurring cycles that …
severe cognitive and behavioral impairments. Circadian rhythms are recurring cycles that …
Exercise as a positive modulator of brain function
KA Alkadhi - Molecular neurobiology, 2018 - Springer
Various forms of exercise have been shown to prevent, restore, or ameliorate a variety of
brain disorders including dementias, Parkinson's disease, chronic stress, thyroid disorders …
brain disorders including dementias, Parkinson's disease, chronic stress, thyroid disorders …
[HTML][HTML] Targeting whole body metabolism and mitochondrial bioenergetics in the drug development for Alzheimer's disease
Aging is by far the most prominent risk factor for Alzheimer's disease (AD), and both aging
and AD are associated with apparent metabolic alterations. As developing effective …
and AD are associated with apparent metabolic alterations. As developing effective …
Chronic functional bowel syndrome enhances gut-brain axis dysfunction, neuroinflammation, cognitive impairment, and vulnerability to dementia
MA Daulatzai - Neurochemical research, 2014 - Springer
The irritable bowel syndrome (IBS) is a common chronic functional gastrointestinal disorder
world wide that lasts for decades. The human gut harbors a diverse population of microbial …
world wide that lasts for decades. The human gut harbors a diverse population of microbial …
Impact of social isolation on the behavioral, functional profiles, and hippocampal atrophy asymmetry in dementia in times of coronavirus pandemic (COVID-19): a …
A Muntsant, L Giménez-Llort - Frontiers in psychiatry, 2020 - frontiersin.org
The impact of COVID-19 on the elderly is devastating, and nursing homes are struggling to
provide the best care to the most fragile. The urgency and severity of the pandemic forces …
provide the best care to the most fragile. The urgency and severity of the pandemic forces …