Therapeutic potential of colchicine in cardiovascular medicine: a pharmacological review

FS Zhang, QZ He, CH Qin, PJ Little, JP Weng… - Acta Pharmacologica …, 2022 - nature.com
Colchicine is an ancient herbal drug derived from Colchicum autumnale. It was first used to
treat familial Mediterranean fever and gout. Based on its unique efficacy as an anti …

Platelets in inflammation and atherogenesis

HM Nording, P Seizer, HF Langer - Frontiers in immunology, 2015 - frontiersin.org
Platelets contribute to processes beyond thrombus formation and may play a so far
underestimated role as an immune cell in various circumstances. This review outlines …

Inflammation-induced thrombosis: mechanisms, disease associations and management

K Aksu, A Donmez, G Keser - Current pharmaceutical design, 2012 - ingentaconnect.com
Although inflammation-induced thrombosis is a well-known entity, its pathogenesis remains
complicated. There are complex interactions between inflammation and hemostasis …

Platelets in atherosclerosis

D Lievens, P von Hundelshausen - Thrombosis and …, 2011 - thieme-connect.com
Beyond obvious functions in haemostasis and thrombosis, platelets are considered to be
essential in proinflammatory surroundings such as atherosclerosis, allergy, rheumatoid …

Purinergic receptors in thrombosis and inflammation

B Hechler, C Gachet - Arteriosclerosis, thrombosis, and vascular …, 2015 - Am Heart Assoc
Under various pathological conditions, including thrombosis and inflammation, extracellular
nucleotide levels may increase because of both active release and passive leakage from …

Antiplatelet drugs: a review of their pharmacology and management in the perioperative period

R Hall, CD Mazer - Anesthesia & Analgesia, 2011 - journals.lww.com
In the normal course of the delivery of care, anesthesiologists encounter many patients who
are receiving drugs that affect platelet function as a fundamental part of primary and …

Immunomodulatory and anti‐inflammatory effects of chondroitin sulphate

P du Souich, AG García, J Vergés… - Journal of cellular and …, 2009 - Wiley Online Library
Biochemistry of chondrotin sulphate• Mechanism of action of chondroitin sulphate‐Effect of
chondroitin sulphate on the chondrocyte‐Effect of chondroitin sulphate on the synovial …

P2 receptors, platelet function and pharmacological implications

C Gachet - Thrombosis and haemostasis, 2008 - thieme-connect.com
ADP and ATP play a crucial role in platelet activation and their receptors are potential
targets for antithrombotic drugs. The ATP-gated cation channel P2X 1 and the two G protein …

Factors affecting the formation and treatment of thrombosis by natural and synthetic compounds

A Lichota, EM Szewczyk, K Gwozdzinski - International journal of …, 2020 - mdpi.com
Venous thromboembolism (VTE) refers to deep vein thrombosis (DVT), whose consequence
may be a pulmonary embolism (PE). Thrombosis is associated with significant morbidity and …

Extracellular nucleotide and nucleoside signaling in vascular and blood disease

M Idzko, D Ferrari, AK Riegel… - Blood, The Journal of …, 2014 - ashpublications.org
Nucleotides and nucleosides—such as adenosine triphosphate (ATP) and adenosine—are
famous for their intracellular roles as building blocks for the genetic code or cellular energy …