Glial-neuronal interactions in pathogenesis and treatment of spinal cord injury

N Lukacova, A Kisucka, K Kiss Bimbova… - International Journal of …, 2021 - mdpi.com
Traumatic spinal cord injury (SCI) elicits an acute inflammatory response which comprises
numerous cell populations. It is driven by the immediate response of macrophages and …

The anti-inflammation property of olfactory ensheathing cells in neural regeneration after spinal cord injury

C Jiang, X Wang, Y Jiang, Z Chen, Y Zhang… - Molecular …, 2022 - Springer
Neural regeneration has troubled investigators worldwide in the past decades. Currently,
cell transplantation emerged as a breakthrough targeted therapy for spinal cord injury (SCI) …

Combination therapy with ultrasound and 2D nanomaterials promotes recovery after spinal cord injury via Piezo1 downregulation

F Zhang, X He, K Dong, L Yang, B Ma, Y Liu… - Journal of …, 2023 - Springer
Spinal cord injury (SCI) causes severe neurological dysfunction and currently has no
effective treatment. Due to the complex pathophysiological processes associated with SCI …

Modified black phosphorus quantum dots promotes spinal cord injury repair by targeting the AKT signaling pathway

DM Xie, C Sun, Q Tu, S Li, Y Zhang… - Journal of Tissue …, 2023 - journals.sagepub.com
Spinal cord injury (SCI) is a serious refractory disease of the central nervous system (CNS),
which mostly caused by high-energy trauma. Existing interventions such as hormone shock …

Neuroinflammation in the evolution of motor function in stroke and trauma patients: treatment and potential biomarkers

A Larrea, A Elexpe, E Díez-Martín, M Torrecilla… - Current Issues in …, 2023 - mdpi.com
Neuroinflammation has a significant impact on different pathologies, such as stroke or spinal
cord injury, intervening in their pathophysiology: expansion, progression, and resolution …

Study of nerve cell regeneration on nanofibers containing cerium oxide nanoparticles in a spinal cord injury model in rats

B Rahimi, Z Behroozi, A Motamednezhad… - Journal of Materials …, 2023 - Springer
Since the CNS is unable to repair itself via neuronal regeneration in adult mammals,
alternative therapies need to be found. The use of cerium oxide nanoparticles to repair …

Curcumin-Containing polyphosphazene nanodrug for Anti-Inflammation and nerve regeneration to improve functional recovery after spinal cord injury

X Su, X Jing, W Jiang, M Li, K Liu, M Teng… - International Journal of …, 2023 - Elsevier
The microenvironment of excessive inflammation and the activation of apoptotic signals are
primary barriers to neurological recovery following spinal cord injury (SCI). Thus, long …

[HTML][HTML] Therapeutic potential of natural compounds from herbs and nutraceuticals in spinal cord injury: Regulation of the mTOR signaling pathway

Y Du, X Cai - Biomedicine & Pharmacotherapy, 2023 - Elsevier
Spinal cord injury (SCI) is a disease in which the spinal cord is subjected to various external
forces that cause it to burst, shift, or, in severe cases, injure the spinal tissue, resulting in …

Wogonin inhibits inflammation and apoptosis through STAT3 signal pathway to promote the recovery of spinal cord injury

W Shao, C Zhang, K Li, Z Lu, Z Zhao, K Gao, C Lv - Brain Research, 2022 - Elsevier
Spinal cord injury (SCI) is a complex central traumatic disease. STAT3 signal transduction
pathway plays an important role in SCI. Wogonin has been reported to exhibit …

Selenium deficiency induces autophagy in chicken bursa of fabricius through ChTLR4/MyD88/NF-κB pathway

R Zhang, Q Liu, R Guo, D Zhang, Y Chen, G Li… - … Trace Element Research, 2022 - Springer
To explore the role of ChTLR4/MyD88/NF-κB signaling pathway on autophagy induced by
selenium (Se) deficiency in the chicken bursa of Fabricius, autophagosome formation in the …