[PDF][PDF] Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses

DM Morens, JK Taubenberger, AS Fauci - Cell Host & Microbe, 2023 - cell.com
Viruses that replicate in the human respiratory mucosa without infecting systemically,
including influenza A, SARS-CoV-2, endemic coronaviruses, RSV, and many other" …

[PDF][PDF] Innate immune and inflammatory responses to SARS-CoV-2: Implications for COVID-19

SA Lowery, A Sariol, S Perlman - Cell host & microbe, 2021 - cell.com
COVID-19 can result in severe disease characterized by significant immunopathology that is
spurred by an exuberant, yet dysregulated, innate immune response with a poor adaptive …

[HTML][HTML] COVID-19 severity correlates with airway epithelium–immune cell interactions identified by single-cell analysis

RL Chua, S Lukassen, S Trump, BP Hennig… - Nature …, 2020 - nature.com
To investigate the immune response and mechanisms associated with severe coronavirus
disease 2019 (COVID-19), we performed single-cell RNA sequencing on nasopharyngeal …

[HTML][HTML] An update on current therapeutic drugs treating COVID-19

R Wu, L Wang, HCD Kuo, A Shannar, R Peter… - Current pharmacology …, 2020 - Springer
The current pandemic of coronavirus disease 2019 (COVID-19) caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) has presented unprecedented …

Transcriptomic characteristics of bronchoalveolar lavage fluid and peripheral blood mononuclear cells in COVID-19 patients

Y Xiong, Y Liu, L Cao, D Wang, M Guo… - Emerging microbes & …, 2020 - Taylor & Francis
Circulating in China and 158 other countries and areas, the ongoing COVID-19 outbreak
has caused devastating mortality and posed a great threat to public health. However, efforts …

[HTML][HTML] Coronavirus infections: Epidemiological, clinical and immunological features and hypotheses

D Raoult, A Zumla, F Locatelli, G Ippolito, G Kroemer - Cell stress, 2020 - ncbi.nlm.nih.gov
Coronaviruses (CoVs) are a large family of enveloped, positive-strand RNA viruses. Four
human CoVs (HCoVs), the non-severe acute respiratory syndrome (SARS)-like HCoVs …

Will children reveal their secret? The coronavirus dilemma

L Cristiani, E Mancino, L Matera… - European respiratory …, 2020 - Eur Respiratory Soc
On 11 March, 2020, a novel human coronavirus, named severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) became pandemic [1]. By 24 March, 372 757 SARS-CoV-2 …

[HTML][HTML] Innate immune evasion by human respiratory RNA viruses

M Kikkert - Journal of innate immunity, 2020 - karger.com
The impact of respiratory virus infections on the health of children and adults can be very
significant. Yet, in contrast to most other childhood infections as well as other viral and …

[PDF][PDF] COVID-19 and the human innate immune system

JL Schultze, AC Aschenbrenner - Cell, 2021 - cell.com
The introduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the
human population represents a tremendous medical and economic crisis. Innate immunity …

Blood molecular markers associated with COVID‐19 immunopathology and multi‐organ damage

YM Chen, Y Zheng, Y Yu, Y Wang, Q Huang… - The EMBO …, 2020 - embopress.org
COVID‐19 is characterized by dysregulated immune responses, metabolic dysfunction and
adverse effects on the function of multiple organs. To understand host responses to COVID …