Rhinovirus induces airway remodeling: what are the physiological consequences?

C Spector, CM De Sanctis, RA Panettieri Jr… - Respiratory …, 2023 - Springer
Background Rhinovirus infections commonly evoke asthma exacerbations in children and
adults. Recurrent asthma exacerbations are associated with injury-repair responses in the …

From virus to inflammation, how influenza promotes lung damage

M Klomp, S Ghosh, S Mohammed… - Journal of leukocyte …, 2021 - academic.oup.com
Despite seasonal vaccines, influenza-related hospitalization and death rates have remained
unchanged over the past 5 years. Influenza pathogenesis has 2 crucial clinical components; …

BCL6 modulates tissue neutrophil survival and exacerbates pulmonary inflammation following influenza virus infection

B Zhu, R Zhang, C Li, L Jiang… - Proceedings of the …, 2019 - National Acad Sciences
Neutrophils are vital for antimicrobial defense; however, their role during viral infection is
less clear. Furthermore, the molecular regulation of neutrophil fate and function at the viral …

[HTML][HTML] Rapid relapse of symptomatic omicron SARS-CoV-2 infection following early suppression with nirmatrelvir/ritonavir

M Charness, K Gupta, G Stack, J Strymish, E Adams… - 2022 - europepmc.org
We describe relapse of COVID-19 symptoms and SARS-CoV-2 viral load following
nirmatrelvir/ritonavir (NM/R) in 10 non-immunocompromised patients aged 31 to 71-years …

Systemic arterial hypertension as a risk factor for the severe form of covid-19: scoping review

AC Ribeiro, SCSA Uehara - Revista de saude publica, 2022 - SciELO Brasil
ABSTRACT OBJECTIVE Identify whether systemic arterial hypertension is a risk factor for
the severe form of covid-19. METHODS This is a scoping review, searches were performed …

Systemic innate and adaptive immune responses to SARS-CoV-2 as it relates to other coronaviruses

P O'Connell, YA Aldhamen - Human Vaccines & …, 2020 - Taylor & Francis
The deadly pandemic caused by the novel coronavirus, Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) represents one of the greatest threats humanity has …

Immunogenetic association underlying severe COVID-19

K McCoy, A Peterson, Y Tian, Y Sang - Vaccines, 2020 - mdpi.com
SARS-CoV2 has caused the current pandemic of new coronavirus disease 2019 (COVID-
19) worldwide. Clinical outcomes of COVID-19 illness range broadly from asymptotic and …

Respiratory RNA viruses

RL Hodinka - Diagnostic Microbiology of the …, 2016 - Wiley Online Library
Viruses account for more episodes of respiratory tract disease than any other microbial
pathogens, and exact a significant toll on society and healthcare systems, leading to …

In vitro models for studying respiratory host–pathogen interactions

SL Barron, J Saez, RM Owens - Advanced Biology, 2021 - Wiley Online Library
Respiratory diseases and lower respiratory tract infections are among the leading cause of
death worldwide and, especially given the recent severe acute respiratory syndrome …

Development of off-the-shelf hematopoietic stem cell-engineered invariant natural killer T cells for COVID-19 therapeutic intervention

YR Li, ZS Dunn, G Garcia Jr, C Carmona… - Stem cell research & …, 2022 - Springer
Background New COVID-19 treatments are desperately needed as case numbers continue
to rise and emergent strains threaten vaccine efficacy. Cell therapy has revolutionized …