Mechanisms of central hypogonadism
TM Barber, I Kyrou, G Kaltsas, AB Grossman… - International Journal of …, 2021 - mdpi.com
Reproductive function depends upon an operational hypothalamo–pituitary–gonadal (HPG)
axis. Due to its role in determining survival versus reproductive strategies, the HPG axis is …
axis. Due to its role in determining survival versus reproductive strategies, the HPG axis is …
Endocrine dysfunction after traumatic brain injury: an ignored clinical syndrome?
C Mahajan, H Prabhakar, F Bilotta - Neurocritical care, 2023 - Springer
Traumatic brain injury (TBI) incurs substantial health and economic burden, as it is the
leading reason for death and disability globally. Endocrine abnormalities are no longer …
leading reason for death and disability globally. Endocrine abnormalities are no longer …
Isolated anterior pituitary dysfunction in adulthood
N Prencipe, L Marinelli, E Varaldo, D Cuboni… - Frontiers in …, 2023 - frontiersin.org
Hypopituitarism is defined as a complete or partial deficiency in one or more pituitary
hormones. Anterior hypopituitarism includes secondary adrenal insufficiency, central …
hormones. Anterior hypopituitarism includes secondary adrenal insufficiency, central …
Traumatic brain injury as frequent cause of hypopituitarism and growth hormone deficiency: epidemiology, diagnosis, and treatment
V Gasco, V Cambria, F Bioletto, E Ghigo… - Frontiers in …, 2021 - frontiersin.org
Traumatic brain injury (TBI)-related hypopituitarism has been recognized as a clinical entity
for more than a century, with the first case being reported in 1918. However, during the 20th …
for more than a century, with the first case being reported in 1918. However, during the 20th …
Neuroinflammation and hypothalamo-pituitary dysfunction: focus of traumatic brain injury
The incidence of traumatic brain injury (TBI) has increased over the last years with an
important impact on public health. Many preclinical and clinical studies identified multiple …
important impact on public health. Many preclinical and clinical studies identified multiple …
Functional overlay model of persistent post-concussion syndrome
I Mavroudis, S Chatzikonstantinou, F Petridis… - Brain Sciences, 2023 - mdpi.com
Persistent post-concussion syndrome (PPCS) is a complex and debilitating condition that
can develop after head concussions or mild traumatic brain injury (mTBI). PPCS is …
can develop after head concussions or mild traumatic brain injury (mTBI). PPCS is …
Plasma phosphorylated tau181 as a biomarker of mild traumatic brain injury: findings from THINC and NCAA-DoD CARE Consortium prospective cohorts
Objective The aim of this study was to investigate phosphorylated tau (p-tau181) protein in
plasma in a cohort of mild traumatic brain injury (mTBI) patients and a cohort of concussed …
plasma in a cohort of mild traumatic brain injury (mTBI) patients and a cohort of concussed …
Growth hormone deficiency following traumatic brain injury in pediatric and adolescent patients: presentation, treatment, and challenges of transitioning from pediatric …
TL Wexler, K Reifschneider, P Backeljauw… - Journal of …, 2023 - liebertpub.com
Traumatic brain injury (TBI) is increasingly recognized, with an incidence of approximately
110 per 100,000 in pediatric populations and 618 per 100,000 in adolescent and adult …
110 per 100,000 in pediatric populations and 618 per 100,000 in adolescent and adult …
Neurobiology of puberty and its disorders
SF Witchel, TM Plant - Handbook of Clinical Neurology, 2021 - Elsevier
Puberty, which in humans is considered to include both gonadarche and adrenarche, is the
period of becoming capable of reproducing sexually and is recognized by maturation of the …
period of becoming capable of reproducing sexually and is recognized by maturation of the …
[HTML][HTML] A consensus on optimization of care in patients with growth hormone deficiency and mild traumatic brain injury
KCJ Yuen, B Masel, MS Jaffee, G O'Shanick… - Growth Hormone & IGF …, 2022 - Elsevier
Abstract Objective/design Approximately 2.9 million children and adults in the US
experience traumatic brain injuries (TBIs) annually, most of which are considered mild. TBI …
experience traumatic brain injuries (TBIs) annually, most of which are considered mild. TBI …