The MYC transcription factor, encoded by the c‐MYC proto‐oncogene, is activated by
growth‐promoting signals, and is a key regulator of biosynthetic and metabolic pathways …

Polyploid cells demonstrate biological plasticity and stress adaptation in evolution;
development; and pathologies, including cardiovascular diseases, neurodegeneration, and …

Replicative stress promotes genomic instability and tumorigenesis but also presents an
effective therapeutic endpoint, rationalizing detailed analysis of pathways that control DNA …

The RUNX family of transcription factors, including RUNX1, RUNX2, and RUNX3, are key
regulators of development and can function as either tumor suppressors or oncogenes in …

Abstract N-acetyltransferase 10 (NAT10) is a nucleolar acetyltransferase and has been
reported to facilitate tumorigenesis in various cancers, but its role in NSCLC and how it is …

Simple Summary Neuroblastoma is a childhood cancer with poor survival and new
therapies are urgently needed, especially for high-risk disease. Here, we demonstrate that …

Some relevant emerging properties of intelligent systems are “adaptation to a changing
environment,”“reaction to unexpected situations,”“capacity of problem solving,” and “ability to …

The transcription factor MYC plays a pivotal role in regulating various cellular processes and
has been implicated in tumorigenesis across multiple cancer types. MYC has emerged as a …

Deregulation of MYC is among the most frequent oncogenic drivers in hepatocellular
carcinoma (HCC). Unfortunately, the clinical success of MYC‐targeted therapies is limited …

DNA replication is a major source of endogenous DNA damage in tumor cells and a key
target of cellular response to genotoxic stress. DNA replication can be deregulated by …