Gastric cancer is the most common malignant tumor in the digestive tract, with very high
morbidity and mortality in developing countries. The pathogenesis of gastric cancer is a …

Gastric cancer is thought to result from a combination of environmental factors and the
accumulation of specific genetic alterations due to increasing genetic instability, and …

Trefoil factor (TFF) 1 is synthesized and secreted by the normal stomach mucosa and by the
gastrointestinal cells of injured tissues. The link between mouse TFF1 inactivation and the …

p16 (CDKN2A) is a member of the INK4 class of cell cycle inhibitors, which is often
dysregulated in cancer. However, the prevalence of p16 expression in different cancer types …

Helicobacter pylori (H. pylori) infections are strongly implicated in human gastric mucosa–
associated diseases. Forkhead box M1 (FoxM1), a key positive regulator of cell proliferation …

Gastric cancer is the fourth most common cancer and the second leading cause of cancer-
related death in the world. Over the past 2 decades, many exciting discoveries regarding the …

Although the considerable progress against gastric cancer, it remains a complex lethal
disease defined by peculiar histological and molecular features. The purpose of the present …

Cell cycle regulators cyclin D1 and cyclin E2 function in G1/S transition by activating
downstream cyclin-dependent kinases. Deregulated expression of these cyclins has been …

Background: There is a lack of consistency regarding the prognostic value of cyclin E
overexpression in gastric cancer (gastric cancer). Our aim was to report on this …

Summary The Cancer Genome Atlas Research Network classified gastric adenocarcinoma
into four molecular subtypes:(1) Epstein-Barr virus–positive (EBV),(2) microsatellite-instable …