[HTML][HTML] Illuminating RNA biology through imaging
RNA processing plays a central role in accurately transmitting genetic information into
functional RNA and protein regulators. To fully appreciate the RNA life-cycle, tools to …
functional RNA and protein regulators. To fully appreciate the RNA life-cycle, tools to …
[HTML][HTML] Poly (A)-binding proteins: multifunctional scaffolds for the post-transcriptional control of gene expression
DA Mangus, MC Evans, A Jacobson - Genome biology, 2003 - Springer
Most eukaryotic mRNAs are subject to considerable post-transcriptional modification,
including capping, splicing, and polyadenylation. The process of polyadenylation adds a …
including capping, splicing, and polyadenylation. The process of polyadenylation adds a …
An improved MS2 system for accurate reporting of the mRNA life cycle
The MS2–MCP system enables researchers to image multiple steps of the mRNA life cycle
with high temporal and spatial resolution. However, for short-lived mRNAs, the tight binding …
with high temporal and spatial resolution. However, for short-lived mRNAs, the tight binding …
A pseudogene long-noncoding-RNA network regulates PTEN transcription and translation in human cells
P Johnsson, A Ackley, L Vidarsdottir, WO Lui… - Nature structural & …, 2013 - nature.com
PTEN is a tumor-suppressor gene that has been shown to be under the regulatory control of
a PTEN pseudogene expressed noncoding RNA, PTENpg1. Here, we characterize a …
a PTEN pseudogene expressed noncoding RNA, PTENpg1. Here, we characterize a …
Movement of eukaryotic mRNAs between polysomes and cytoplasmic processing bodies
M Brengues, D Teixeira, R Parker - Science, 2005 - science.org
Eukaryotic cells contain nontranslating messenger RNA concentrated in P-bodies, which are
sites where the mRNA can be decapped and degraded. We present evidence that mRNA …
sites where the mRNA can be decapped and degraded. We present evidence that mRNA …
Processing bodies require RNA for assembly and contain nontranslating mRNAs
D Teixeira, U Sheth, MA Valencia-Sanchez… - Rna, 2005 - rnajournal.cshlp.org
Recent experiments have defined cytoplasmic foci, referred to as processing bodies (P-
bodies), wherein mRNA decay factors are concentrated and where mRNA decay can occur …
bodies), wherein mRNA decay factors are concentrated and where mRNA decay can occur …
Nucleocytoplasmic transport: taking an inventory
H Fried, U Kutay - Cellular and Molecular Life Sciences CMLS, 2003 - Springer
In eukaryotic cells, the enclosure of the genetic information in the nucleus allows the spatial
and temporal separation of DNA replication and transcription from cytoplasmic protein …
and temporal separation of DNA replication and transcription from cytoplasmic protein …
Messenger RNA targeting to endoplasmic reticulum stress signalling sites
Deficiencies in the protein-folding capacity of the endoplasmic reticulum (ER) in all
eukaryotic cells lead to ER stress and trigger the unfolded protein response (UPR),,. ER …
eukaryotic cells lead to ER stress and trigger the unfolded protein response (UPR),,. ER …
In-line probing analysis of riboswitches
EE Regulski, RR Breaker - Post-transcriptional gene regulation, 2008 - Springer
Riboswitches are intricate, metabolite-binding RNA structures found in the non-coding
regions of mRNA. Allosteric changes in the riboswitch that are induced by metabolite …
regions of mRNA. Allosteric changes in the riboswitch that are induced by metabolite …
mRNA nuclear export at a glance
SR Carmody, SR Wente - Journal of cell science, 2009 - journals.biologists.com
Eukaryotic gene expression is controlled by multiple mechanisms, and its regulation is
central for physiological responses to extracellular and intracellular signals. An essential …
central for physiological responses to extracellular and intracellular signals. An essential …