Conservative medical management of chronic suppurative otitis media (CSOM) is an
important step in achieving a dry ear. Topical antibiotic ear drops and aural toilet form the …

To assess the safety of topical agents in the middle ear, animal studies were reviewed.
Compared with aminoglycoside-containing preparations, which caused significant loss of …

The objectives of the study were to determine the effectiveness and incidence of adverse
events of ofloxacin otic solution for suppurative otitis media compared with other treatments …

A bacteriological study on 161 consecutive out-patients presenting with otorrhoea was
performed prospectively at a local teaching hospital in Taiwan between August 2000 and …

BACKGROUND: Quinolone-induced mutagenesis in the Salmonella typhimurium hisG48
strains suggests that these antibiotics are oxygen free radical generators. The use of β …

The choice of antimicrobial agents used to treat Pseudomonas aeruginosa infections of the
ear is quite empiric. Yet in spite of this, very little has been published examining …

Active chronic suppurative otitis media poses a management problem when patients are
being considered for surgical treatment. Topical antibiotics have demonstrated varying …

There has been a steady increase in the number of cases of methicillin-resistant
Staphylococcus aureus (MRSA) otorrhoea; this is a growing concern. The purpose of this …

Objectives--Although community-acquired methicillin-resistant Staphylococcus aureus
(MRSA) infections have recently become an increasing problem in various fields of …

The role of corticosteroid in patients of chronic suppurative otitis media (CSOM) is unknown.
In the present study, the efficacy and safety of ofloxacin alone (OA) and the ofloxacin+ …