Albumin uptake and processing by the proximal tubule: Physiological, pathological, and therapeutic implications

BA Molitoris, RM Sandoval, SPS Yadav… - Physiological …, 2022 - journals.physiology.org
For nearly 50 years the proximal tubule (PT) has been known to reabsorb, process, and
either catabolize or transcytose albumin from the glomerular filtrate. Innovative techniques …

[HTML][HTML] Serum albumin: a multifaced enzyme

G De Simone, A di Masi, P Ascenzi - International Journal of Molecular …, 2021 - mdpi.com
Human serum albumin (HSA) is the most abundant protein in plasma, contributing actively to
oncotic pressure maintenance and fluid distribution between body compartments. HSA acts …

Sulfhydryl groups as targets of mercury toxicity

OP Ajsuvakova, AA Tinkov, M Aschner… - Coordination chemistry …, 2020 - Elsevier
The present study addresses existing data on the affinity and conjugation of sulfhydryl (thiol;-
SH) groups of low-and high-molecular-weight biological ligands with mercury (Hg). The …

Human serum albumin: from bench to bedside

G Fanali, A Di Masi, V Trezza, M Marino… - Molecular aspects of …, 2012 - Elsevier
Human serum albumin (HSA), the most abundant protein in plasma, is a monomeric multi-
domain macromolecule, representing the main determinant of plasma oncotic pressure and …

Structures of bovine, equine and leporine serum albumin

A Bujacz - Acta Crystallographica Section D: Biological …, 2012 - journals.iucr.org
Serum albumin first appeared in early vertebrates and is present in the plasma of all
mammals. Its canonical structure supported by a conserved set of disulfide bridges is …

Albumin and its application in drug delivery

D Sleep - Expert opinion on drug delivery, 2015 - Taylor & Francis
Introduction: Rapid clearance of drugs from the body results in short therapeutic half-life and
is an integral property of many protein and peptide-based drugs. To maintain the desired …

A comprehensive review on flavanones, the major citrus polyphenols

MK Khan, O Dangles - Journal of Food Composition and Analysis, 2014 - Elsevier
The consumption of Citrus fruits and juices has been widely investigated for its possible role
in the prevention of cardiovascular disease and cancer. These beneficial effects are mainly …

Binding of erucic acid with human serum albumin using a spectroscopic and molecular docking study

G Rabbani, MH Baig, AT Jan, EJ Lee, MV Khan… - International journal of …, 2017 - Elsevier
Erucic acid (EA) is one of the key fatty acids usually found in canola oil, mustard oil and
rapeseed oil. Consumption of EA in primates was found to cause myocardial lipidosis and …

[HTML][HTML] Overview of albumin and its purification methods

R Raoufinia, A Mota, N Keyhanvar, F Safari… - Advanced …, 2016 - ncbi.nlm.nih.gov
As the most frequent plasma protein, albumin constitutes more than 50% of the serum
proteins in healthy individuals. It has a key role in oncotic pressure maintenance and it is …

Interactions between Antimalarial Indolone-N-oxide Derivatives and Human Serum Albumin

N Ibrahim, H Ibrahim, S Kim, JP Nallet… - …, 2010 - ACS Publications
The binding affinity of human serum albumin (HSA) to three antimalarial indolone-N-oxide
derivatives, INODs, was investigated under simulated physiological conditions using …