Global functions of O‐glycosylation: promises and challenges in O‐glycobiology
HH Wandall, MAI Nielsen, S King‐Smith… - The FEBS …, 2021 - Wiley Online Library
Mucin type O‐glycosylation is one of the most diverse types of glycosylation, playing
essential roles in tissue development and homeostasis. In complex organisms, O‐GalNAc …
essential roles in tissue development and homeostasis. In complex organisms, O‐GalNAc …
[HTML][HTML] Sialylated glycan bindings from SARS-CoV-2 spike protein to blood and endothelial cells govern the severe morbidities of COVID-19
DE Scheim, P Vottero, AD Santin, AG Hirsh - International journal of …, 2023 - mdpi.com
Consistent with well-established biochemical properties of coronaviruses, sialylated glycan
attachments between SARS-CoV-2 spike protein (SP) and host cells are key to the virus's …
attachments between SARS-CoV-2 spike protein (SP) and host cells are key to the virus's …
[HTML][HTML] Plasmodium falciparum is evolving to escape malaria rapid diagnostic tests in Ethiopia
SM Feleke, EN Reichert, H Mohammed… - Nature …, 2021 - nature.com
In Africa, most rapid diagnostic tests (RDTs) for falciparum malaria recognize histidine-rich
protein 2 antigen. Plasmodium falciparum parasites lacking histidine-rich protein 2 (pfhrp2) …
protein 2 antigen. Plasmodium falciparum parasites lacking histidine-rich protein 2 (pfhrp2) …
[HTML][HTML] Sialic acids as receptors for pathogens
P Burzyńska, ŁF Sobala, K Mikołajczyk, M Jodłowska… - Biomolecules, 2021 - mdpi.com
Carbohydrates have long been known to mediate intracellular interactions, whether within
one organism or between different organisms. Sialic acids (Sias) are carbohydrates that …
one organism or between different organisms. Sialic acids (Sias) are carbohydrates that …
[HTML][HTML] A deadly embrace: Hemagglutination mediated by SARS-CoV-2 spike protein at its 22 N-glycosylation sites, red blood cell surface sialoglycoproteins, and …
DE Scheim - International journal of molecular sciences, 2022 - mdpi.com
Rouleaux (stacked clumps) of red blood cells (RBCs) observed in the blood of COVID-19
patients in three studies call attention to the properties of several enveloped virus strains …
patients in three studies call attention to the properties of several enveloped virus strains …
A world free of malaria: It is time for Africa to actively champion and take leadership of elimination and eradication strategies
The global burden of malaria seems unabated. Africa carries the greatest burden accounting
for over 95% of the annual cases of malaria. For the vision of a world free of malaria by …
for over 95% of the annual cases of malaria. For the vision of a world free of malaria by …
Nanocarrier based active targeting strategies against erythrocytic stage of malaria
Abstract The Global Technical Strategy for Malaria 2016–2030 aims to achieve a 90%
reduction in malaria cases, and strategic planning and execution are crucial for …
reduction in malaria cases, and strategic planning and execution are crucial for …
Mucin-Type O-GalNAc Glycosylation in Health and Disease
I Bagdonaite, EMH Pallesen, MI Nielsen… - The role of glycosylation …, 2021 - Springer
Mucin-type GalNAc O-glycosylation is one of the most abundant and unique post-
translational modifications. The combination of proteome-wide mapping of GalNAc O …
translational modifications. The combination of proteome-wide mapping of GalNAc O …
[HTML][HTML] Escaping the enemy's bullets: an update on how malaria parasites evade host immune response
Malaria continues to cause untold hardship to inhabitants of malaria-endemic regions,
causing significant morbidity and mortality that severely impact global health and the …
causing significant morbidity and mortality that severely impact global health and the …
[HTML][HTML] In silico analysis of the multi-targeted mode of action of ivermectin and related compounds
Some clinical studies have indicated activity of ivermectin, a macrocyclic lactone, against
COVID-19, but a biological mechanism initially proposed for this anti-viral effect is not …
COVID-19, but a biological mechanism initially proposed for this anti-viral effect is not …