Oncologic benefits of neoadjuvant treatment versus upfront surgery in borderline resectable pancreatic cancer: a systematic review and meta-analysis

HS Jung, HS Kim, JS Kang, YH Kang, HJ Sohn, Y Byun… - Cancers, 2022 - mdpi.com
Simple Summary Borderline resectable pancreatic cancer (BRPC) has been primarily
indicated for neoadjuvant treatment (NAT) in the last decade. This study is the updated meta …

[HTML][HTML] Role of imaging in evaluating the response after neoadjuvant treatment for pancreatic ductal adenocarcinoma

Y Zhang, ZX Huang, B Song - World Journal of Gastroenterology, 2021 - ncbi.nlm.nih.gov
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignancy. Despite the
development of multimodality treatments, including surgical resection, radiotherapy, and …

Serum DUPAN-2 could be an alternative biological marker for CA19-9 nonsecretors with pancreatic cancer

K Omiya, A Oba, Y Inoue, K Kobayashi, YHA Wu… - Annals of …, 2023 - journals.lww.com
Objective: This study investigates the use of serum DUPAN-2 in predicting the PC
progression in CA19-9 nonsecretors. Background: Although we previously reported that …

[HTML][HTML] PD-1 blockade plus chemoradiotherapy as preoperative therapy for patients with BRPC/LAPC: A biomolecular exploratory, phase II trial

J Du, C Lu, L Mao, Y Zhu, W Kong, S Shen, M Tang… - Cell Reports …, 2023 - cell.com
This is a phase II study of PD-1 blockade plus chemoradiotherapy as preoperative therapy
for patients with locally advanced or borderline resectable pancreatic cancer (LAPC or …

Early-onset pancreatic cancer: clinical characteristics and survival outcomes

T Takeda, T Sasaki, Y Inoue, T Okamoto, C Mori, T Mie… - Pancreatology, 2022 - Elsevier
Background Early-onset pancreatic cancer (≤ 50 years, EOPC) is uncommon. This study
aims to characterize the clinical and survival characteristics of EOPC in comparison to late …

High CA19-9 level in resectable pancreatic cancer is a potential indication of neoadjuvant treatment

Y Ushida, Y Inoue, H Ito, A Oba, Y Mise, Y Ono, T Sato… - Pancreatology, 2021 - Elsevier
Background Previous studies on borderline resectable (BR) pancreatic cancer (PC)
included patients with heterogenous preoperative states; however, the definition of …

Prediction of recurrence pattern of pancreatic cancer post-pancreatic surgery using histology-based supervised machine learning algorithms: a single-center …

K Hayashi, Y Ono, M Takamatsu, A Oba, H Ito… - Annals of Surgical …, 2022 - Springer
Background Patients with pancreatic cancer (PC) have poor prognosis and a high incidence
of recurrence. Since further treatment is applicable for specific recurrent events, it is …

Efficacy and safety of neoadjuvant nab‐paclitaxel plus gemcitabine therapy in patients with borderline resectable pancreatic cancer: A multicenter single‐arm phase II …

K Okada, K Kimura, YI Yamashita… - Annals of …, 2023 - Wiley Online Library
Background Nab‐paclitaxel plus gemcitabine is a standard treatment for metastatic/locally
advanced pancreatic cancer. The effectiveness of neoadjuvant therapy with nab‐paclitaxel …

A prospective multicenter phase II trial of neoadjuvant chemotherapy with gemcitabine plus nab-paclitaxel for borderline resectable pancreatic cancer with arterial …

N Ikenaga, Y Miyasaka, T Ohtsuka, K Nakata… - Annals of surgical …, 2023 - Springer
Background Only two clinical trials have shown the effects of neoadjuvant treatment for
borderline resectable pancreatic cancer with arterial involvement (BRPC-A). Here, we aimed …

Preoperative prediction of long-term survival after surgery in patients with resectable pancreatic ductal adenocarcinoma

T Konishi, S Takano, T Takayashiki, D Suzuki… - Annals of Surgical …, 2024 - Springer
Background Although some clinical trials have demonstrated the benefits of neoadjuvant
therapy for resectable pancreatic ductal adenocarcinoma (PDAC), its optimal candidate has …