Viral oncology: molecular biology and pathogenesis
UN Mui, CT Haley, SK Tyring - Journal of clinical medicine, 2017 - mdpi.com
Oncoviruses are implicated in approximately 12% of all human cancers. A large number of
the world's population harbors at least one of these oncoviruses, but only a small proportion …
the world's population harbors at least one of these oncoviruses, but only a small proportion …
Progress on Ras/MAPK signaling research and targeting in blood and solid cancers
M Dillon, A Lopez, E Lin, D Sales, R Perets, P Jain - Cancers, 2021 - mdpi.com
Simple Summary The Ras-Raf-MEK-ERK signaling pathway is responsible for regulating
cell proliferation, differentiation, and survival. Overexpression and overactivation of …
cell proliferation, differentiation, and survival. Overexpression and overactivation of …
Drug repurposing for viral cancers: a paradigm of machine learning, deep learning, and virtual screening‐based approaches
Cancer management is major concern of health organizations and viral cancers account for
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …
approximately 15.4% of all known human cancers. Due to large number of patients, efficient …
Human T cell leukemia virus type 1: persistence and pathogenesis
CRM Bangham - Annual review of immunology, 2018 - annualreviews.org
Human T cell leukemia virus type 1 (HTLV-1), also known as human T lymphotropic virus
type 1, was the first exogenous human retrovirus discovered. Unlike the distantly related …
type 1, was the first exogenous human retrovirus discovered. Unlike the distantly related …
More than just oncogenes: mechanisms of tumorigenesis by human viruses
Highlights•Viral infections cause approximately 12% of all human cancers.•Viral cancers
represent rare outcomes of frequent infections.•Oncogenicity of viral proteins reflects their …
represent rare outcomes of frequent infections.•Oncogenicity of viral proteins reflects their …
Equivocal, explicit and emergent actions of PKC isoforms in cancer
PJ Parker, SJ Brown, V Calleja, P Chakravarty… - Nature Reviews …, 2021 - nature.com
The maturing mutational landscape of cancer genomes, the development and application of
clinical interventions and evolving insights into tumour-associated functions reveal …
clinical interventions and evolving insights into tumour-associated functions reveal …
Co-Infection and Cancer: Host–Pathogen Interaction between Dendritic Cells and HIV-1, HTLV-1, and Other Oncogenic Viruses
Dendritic cells (DCs) function as a link between innate and adaptive immune responses.
Retroviruses HIV-1 and HTLV-1 modulate DCs to their advantage and utilize them to …
Retroviruses HIV-1 and HTLV-1 modulate DCs to their advantage and utilize them to …
Adult T-cell leukemia and lymphoma in French Guiana: a retrospective analysis with real-life data from 2009 to 2019
K Abdelmoumen, KD Alsibai, S Rabier… - The Lancet Regional …, 2023 - thelancet.com
Background Adult T-cell leukemia/lymphoma (ATL), one of the most aggressive cancers in
the world, occurs in 5% of the 10 million people living with HTLV-1 worldwide. French …
the world, occurs in 5% of the 10 million people living with HTLV-1 worldwide. French …
Molecular evidence of viral DNA in non-small cell lung cancer and non-neoplastic lung
LA Robinson, CJ Jaing, C Pierce Campbell… - British journal of …, 2016 - nature.com
Background: Although∼ 20% of human cancers are caused by microorganisms, only
suspicion exists for a microbial cause of lung cancer. Potential infectious agents were …
suspicion exists for a microbial cause of lung cancer. Potential infectious agents were …
Adult T-cell leukemia/lymphoma
N Mehta-Shah, L Ratner, SM Horwitz - Journal of oncology practice, 2017 - ascopubs.org
Adult T-cell lymphoma/leukemia (ATL) is a rare T-cell lymphoproliferative neoplasm caused
by human T-lymphotrophic virus 1. In its more common, aggressive forms, ATL carries one of …
by human T-lymphotrophic virus 1. In its more common, aggressive forms, ATL carries one of …