Abstract A biallelic G (TNF1 allele) to A (TNF2 allele) polymorphism 308 nucleotides
upstream from the transcription initiation site in the tumor necrosis factor (TNF) promoter is …

Apolipoprotein AI (apoA-I) and high-density lipoproteins (HDL) mediate reverse cholesterol
transport out of cells. Furthermore, HDL has additional protective functions, which include …

The tumor necrosis factor (TNF) alpha gene lies within the class III region of the major
histocompatibility complex (MHC), telomeric to the class II and centromeric to the class I …

Objective. The genetic factors that predispose to the development of juvenile rheumatoid
arthritis (JRA) and its complications are not completely understood. The cytokine interleukin …

Overexpression of plasma apolipoprotein CIII (apo CIII) causes hypertriglyceridemia in
transgenic mice. A genetically variant form of the human apo CIII promoter, containing five …

In this work, we explored the existence of genetic variants within the apolipoprotein E gene
transcriptional regulatory region, using a denaturing gradient gel electrophoresis screening …

Background: A common G-to-A substitution in the promoter area (− 75 base pairs) of the
apolipoprotein AI gene (APOA1) has been described. The A allele was shown to be …

Five DNA polymorphisms were detected in the promoter of the apolipoprotein CIII gene of a
type III hyperlipidemic subject with severe hypertriglyceridemia (HTG). The polymorphic sites …

While the ε4 allele of apolipoprotein E (APOE, gene; ApoE, protein) is widely accepted as a
major genetic risk factor for the late onset form of Alzheimer's disease (AD), recent evidence …

Ultraviolet irradiation stimulates keratinocytes and dermal fibroblasts to release cytokines
involved in apoptosis and immunomodulation, such as tumor necrosis factor-α and …